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LITHIUM WORLDWIDE SURVEY16, 20ALSFRS-R
scale calculation
[0=worst, 48=best]

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#Forum name or
1st name		FromAgeGenderBlood type
(ABO/Rh)		DXALSFRS-R
at DX
[0=worst, 48=best]		ALS [1]On RilutekRilutek doseLithium STARTLithium STOPLithium RESTARTLithium formLithium trade nameLithium dose
#1		Lithium dose
#2		DATE
change dose #2 		Lithium dose
#3		DATE
change dose #3 		Lithium dose
#4		DATE
change dose #4 		Lithium dose
#5		DATE
change dose #5 		LAST
LITHIUM DOSE		LAST DATE
CHANGE DOSE 		Level #1
mmoL/L		Date #1Level #2
mmoL/L		Date #2Level #3
mmoL/L		Date #3Level #4
mmoL/L		Date #4Level #5
mmoL/L		Date #5LAST LEVEL
mmoL/L		LAST DATEDATE reached
0.4 - 0.6 mmoL/L 		Side Effects
overall		Improvements
overall		at DXat Li start1st mth2nd mth3rd mth4th
mth		5th
mth		6th
mth		additional pointdateMeds and SupplementsPhysical Therapies
and others		Comments overallComments - after 1st month
on lithium		Comments - after 2nd month
on lithium		Comments - after 3rd month
on lithium		Comments - after 4th month
on lithium		Comments - after 5th month
on lithium		Comments - after 6th month
on lithium

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P.S. We are now in collaboration with Patients Like Me. We encourage participants in our study to also start a profile at their website http://www.patientslikeme.com/welcome/community/als

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1Humberto MacedoBrazil, Brasília42MA+March-0745sALS/limbYes50 mg 2x/dayDecember 25, 2007September 29, 2008CarbonateCarbolitium150 mg 2x/day150 mg 3x/dayJanuary 17, 2008300 mg 2x/dayFebruary 19, 2008150 mg 3x/dayMarch 3, 2008150 mg 2x/dayApril 18, 2008150 mg/dayJuly 6, 20080.2January 4, 20080.2January 16, 20080.4January 31, 20080.3February 18, 20080.5February 25, 20080.2July 18, 2008January 31, 2008Dry mouth during sleep, slight headache(went away when I started taking lithium just after meals), increased fasciculationsnone4525252522222020Vit.E 1200mg/day - Vit.B12 subl./day - Ômega3/DHA 1gr/day – start creatine 5gr/day (apr-28-08) - start Mass Hyper Dyn (super calorie) and Nutren Active (jun-06-08)Physio 3x/week, speech 1x/week, acupuncture 2x/month, nutritionist 1x/monthon rilutek for 12 months, baclofen 20mg/day, memantine 10mg/day since jan 1st (stopped 17/jan), anafranil 50mg/day, vaccine pneumo23 on jan-4-08, diazepam 5mgStable!Stable!walking becomes difficult and some drooling has appearedSame as 3rd mthback to 300 mg/daysame as last mth and stable

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2Veronica TownsendUSA, Michigan38FO+November-0542sALSYes50 mg 2x/dayDecember 26, 2007Carbonate150 mg 1x/day150 mg 2x/dayJanuary 24, 2008150 mg 3x/dayMarch 18, 2008600 mg/dayMay 29, 20080.2January 9, 20080.1January 16, 20080.2March 10, 20080.5June 10, 2008June 10, 2008strong increased urination, increase in fasciculationsnone38383838373736Had to go off for one week because of frequent/uncontrollable urination. Brought under control with ditropan and Imipramine; back on lithiumfasciculations next to nothing nowwent off of lithium for two weeks after stressful travel; fascics came back; went back on and fascics went away againHaving a good feeling in hands and arms

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3Chris PerdulovskiAustralia 56MAugust-0745fALSYes50 mg 2x/dayDecember 12, 2007May 17, 2005June 13, 2008Carbonate250 mg 3x/day250 mg 3x/dayJanuary 10, 20083 1/2 250 mg/dayJanuary 29, 2008250 mg 4x/day1250 mg/dayMay500 mg/dayJune 13, 20080.20.34January 29, 20080.41February 12, 20080.39?0.5May, 2008February 12, 2008nonenone454545454741on rilutek for 6 monthsstopped lithium on May 17. Was on dosage of 1250 mg/day, blood level 0.5, felt very tired.

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4Ferdinand TriemerGermany67MJuly-0644sALSYes50 mg 2x/dayDecember 27, 2007June 17, 2008CarbonateQuilonum R200 mg 2x/day0.46January 14, 20080.46January 20, 20080.48April 7, 20080.51May 27, 2008January 14, 2008increased fasciculations - noticed after two weeks - More weakness in knees, increased urination, irregular bowel movements. Could not tolerate 1250 mg/day dosage
none443537363534COQ-10 400MG, VIT-E 400 Mu, Alpha Lipoic Acid 300 MG, VIT-C 100 MGon rilutek for 11monthsStopped on June 17 because no improvement; feels like lithium is making things worse.

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5Brian RintoulCanada52MApril-0540sALSYes50 mg 2x/dayDecember 22, 2007July 18, 2008150 mg 2x/day150 mg 3x/dayFebruary 22, 20080.35January 10, 20080.24February 11, 20080.33March 3, 20080.38April 14, 20080.34May 14, 2008skin irritation like mosquito bitesnone1077776On rilutek 2.5years

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6Steve B.USA, California61MO-October-0538sALSYes50 mgqdDecember 20, 2007150 mg bid450 mg600 mg/dayMarch 11, 20080.4January 7, 20080.3February 11, 20080.5March 31, 2008January 7, 2008much weaker legsmore energy?3826252525252524Diaphragm Pacer Nov12, 2007 - walking more difficulthands and neck weaker, breathing stableFRS same but walking & strength sig. impaired. Increased hypoglycemia, tremor, supplementing diet with ensure.

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7Ty AsselsineUSA55FSeptember-0645lower MNDNoDecember 18, 2007March 31, 2008150 mg 2x/day600 mg/dayJanuary 8, 2008<0.2no side effectsnone40394035none

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8David AttardMalta45MJanuary-0748sALSNoDecember 9, 2007200 mg 2x/day300 mg 2x/dayFebruary 9, 2008400 mg/dayMarch 15, 2008600 mg/day0.42January 9, 20080.44February 19, 20080.4March 15, 20080.34March 25, 2008January 9, 2008diarrhea, loss of appetite, fatigue at 600 mg/day; dropped back to 400 mg/daynone483025creatine 1000 mg/cq10 -60 mg/ b12 500mg/ astralagus 1500mg dailynone

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9William HirtUSA64MJanuary-0747sALS/BulbarYes50 mg 2x/dayNovember 21, 2007Carbonate600 mg 1x/day750 mg/dayJanuary 7, 2008900 mg/dayJanuary 26, 2008750 mg/dayJanuary 30, 2008900 mg/dayFebruary 12, 20080.30.37January 18, 20080.46February 1, 20080.33February 11, 20080.61February 25, 20080.41March 3, 2008February 1, 2008noneless fasciculation?343435353432Multivitamin, CoQ10, NAC, grapeseed extract, milk thistle, sphingolin, flaxseed oil, fish oil, testosterone injections, HGH, glutathione infusionsstarted on 300mg, increased to 450 at 12/12 and to 600 at 12/31

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10Hanns RiedererUSA, California38MJune-0540sALSNoDecember 16, 2007Carbonate150 mg 2x/day450mgJanuary 15, 2008600mgFebruary 1, 2008450mgMarch 15, 2008450mg
0,16January 15, 20080,32February 1, 20080,4February 7, 20080.35April 1, 20080.2June 20, 2008February 7, 2008more saliva, more sluring of speech right after taking itless cramps & spasticity, 4025252525242424none

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11David VirdenUSA - Mass.58MOctober-0646sALS/BulbarYes50 mg 2x/dayDecember 15, 2007April 13, 2008OrotateAdvanced Research600 mg 1x/day720 mg/dayJanuary 26, 2008840 mg/day720 mg/dayFebruary 15, 20080.30.3February 25, 2008at 1200 mg/day had diarrhea, weakness in hands, ill feeling. Better after dropping to 480 mg/day lithium orotateslite463033343311taking 120 mg lithium orotate pills I started slow on the Lithium at 240mg per day but increased it slowlystopped lithium while in hospital for 3 weeks for feeding tube and pneumonia

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12Sagit DrishnerIsrael36FJanuary-04sALS/LimbNoDecember 24, 2007300 mg 1x/daySkin irritation, severe itching right hand digits?After blood check for Lithium levels, may increase to more than 300 mg/day

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13Mikko KehusmaaFinland30MOctober-0745ALS/BulbarNoJanuary 3, 2008CarbonateLito150 mg 2x/day150 mg 3x/dayJanuary 17, 2008300 mg 2x/dayFebruary 7, 2008150 mg 4x/dayFebruary 28, 2008150 mg 3x/dayApril <0.2January 9, 2008<0.2January 16, 2008<0.2January 24, 20080.2January 31, 2008<0.2February 7, 20080.4March 6, 2008March 6, 2008Non. I had more saliva and more fasciculations at beginning but not anymore.Better function/power on my legs (can bicycle 10km), better strength in m left hand, better sleep at night, more energy4539424444424037Physio 1x/week, speech 1x/week, voice massage 1x/weekAfter two blood check, increase the dose to 3x150mg/day at 17.1.2008 (orginal 2x150mg/day)My speech has been little bit slurred but I think that its because there has been long delays in my voice massage therapy. Also my fingers has been more stiff but my FRS score is still 44 and no side effects.worse clonus and hands. Excess saliva problem decreased after lowering dosage to 150 mg 3x.daychanging between doses of 300 /450 mg/day, blood level around 0.2 - 0.3

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14Jim Mong USA, Michigan59MSeptember-0745sALS/BulbarYes50 mg 2x/dayDecember 21, 2007CarbonateRoxane150 mg 3x/day150 mg 3x/dayJanuary 16, 2008450 mg 2x/dayJanuary 25, 20080.2January 9, 20080.2January 25, 20080.4January 6, 2008January 6, 2008increased saliva and fasciculation, taste in mouthslight imprv. In R foot45393939Vit - B cmplx, B12, C1000, D, E, Omega/3 3000mg, CoQ10 1200, Multi Min, DMAE, HGH, GlyconutrientStretching exercising @ home, massage therapy 2x/mo chiropractor 2/wkStarting 450mm today, 150 3x/day 1/11/08Feels weaker but not by a full ALSFRS-R point

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15Edward W. EsparzaUSA, Chicago49MSeptember-05sALSNoDecember 19, 2007March 19, 2008Carbonate150 mg 1x/daydry mouth during sleep-?maybe, not sure-? expected increase to 300mg dailyafter next week's M.D. appointmentStopped lithium due to breathing diffficulties and nausea

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16EJWUSA, Montana46FO+December-0647sALS/LimbNoFebruary 29, 2008Carbonate150 mg 2x/day150 mg 3x/dayApril 8, 20080.4March 12, 20080.3April 3, 20080.4April 23, 2008March 12, 2008Dry mouth during the night and muscle cramps -- no more dry mouth or muscle crampsmore flexibility and function in fingers and toes47394039353737CoQ10 800 mg/day, Vitamin E, 1000 mg/day, Vit C, 200 mg/day, Alpha lipoic acid, 300 mg/day, ferrous gluconate 100 mg/day, vitamin B12, vicodin 500 Physical Therapy 1x/weeknonebit of improvement in hands, can wiggle toes and move feet slightly.am able to anke to move a bit now, toes are moving more and without effort.

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17Bill HernUSA, MN51MNovember-0647Yes50 mg 2x/day
December 9, 2007300 mg 2x/day0.7December 15, 20070.55January 22, 2008December 15, 200747292929292929pseudo-bulbar ALS -- more upper neuron involvement

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18SRALCanada63FAugust-0743UMND/bulbarNoJanuary 6, 2008June 28, 2008Carbonate150 mg 2x/day150 mg 3x/dayJanuary 22, 2008150 mg 4x/day
February 11, 2008450 mg/dayApril 5, 20080.2January 12, 2008>0.2January 18, 20080.2February 5, 20080.38March 24, 3008increased fatigue on 1st day and continued increased salivanone4341404040404040vit E 800mg/day, vit B12 subl/day, vit D 1000mg/day, vit C, milk thistlestrength exercises at homeslower and stair climbing harder but not full FRS ptsame FRS but slower and muscle loss in calvesLithium stopped because not effective at slowing progression

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19APFUSA - California63MAugust 200746sALS/limbNoJanuary 4, 2008June 20, 2008Carbonate150 mg 2x/day150 mg 3x/dayJanuary 18, 2008150 mg 4x/dayJanuary 30, 2008750 mg/dayFebruary 5, 2008900 mg/dayFebruary 12, 2008600 mg/dayMay 9, 20080.19January 14, 20080.24January 23, 20080.32February 4, 20080.38February 11, 20080.42February 18, 20080.52February 26, 2008February 18, 2008foot pain on first daynone4640393736342828noneTapering lithium down by 150 mg/week starting June 4, 2008, after consultation with doctor -- lithium not working.

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20Jill C.USA59FJune 200645sALS/bulbarNoDecember 5, 2007April 7, 2008April 25, 2008Carbonate150 mg 2x/day450 mg/dayJanuary300 mg/dayFebruary 16, 20080.3January 8, 20080.9February 8, 20080.3March 21, 20080.4March 24, 2008February 8, 2008none434140403940increased swallowing dif; temporarily stopping Li

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21Guenther B.Germany55MA+January 200745Yes50 mg 2x/dayJanuary 9, 2008CarbonateHypnorex retard200 mg 2x/day400 mg 2x/dayJanuary 30,2008400 mg 2x/dayFebruary 13,20081200 mg/dayMarch 5, 20081200 mg/dayApril 9, 20081200 mg/day1000 mg/day0.23January 29,20080.42February 13,20080.38March 4,20080,6March 27, 20080,51April 11,2008December 30, 1899May 24, 2008February 13, 2008slight trempling of the handsnone4545454543434342vit E 1000mg/dayphysio 2x/week

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22David SaundersUSA/New Jersey44MA+March 200748sALS/limbNoJanuary 10, 2008Carbonate150 mg 2x/day300 mg 2x/dayJanuary 23,2008300 mg 2x/dayFebruary 20,2008300 mg 2x/dayMarch 17, 2008300 mg/dayMay 21, 2008<.01January 22,20080.3January 30, 20080.5February 20, 20080.5March 17, 2008February 20, 2008Itchy Feet, low thyroid - need to see Dr. and increase synthroidMore energy, overall improvment48393939363333CoQ10, Vit E, Multi Vit, Synthroid, Vit C, Physio 2x / week, Home exersise, accupuncture, streachingfeel overall good, minor side effects are gonefeet swellingfeet very swollen and purple. Decreased swelling after lowering dose from 600 to 300 mg/day. Breathing worsened over last 6 months.Cut down to 300/day for two weeks, now back up to 600/day. Feet swollen.

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23AlbertSwedenSweden58MSept. 200644sALS/bulbarYes50 mg 2x/day
January 10, 2008SulphateLithionit42 mg/day42 mg 2x/dayJanuary 17, 200842 mg 3x/dayJanuary 30, 20084 x 42 mg/dayFebruary 8, 20085 x 42 mg/dayMarch 3, 20080.1January 17, 20080.2January 30, 20080.3February 8, 20080.3February 27, 20080.6March 18, 20080.6March 18, 2009March 18, 2008loose bowel movements at dose increasenone442222211915CoQ10 600mg/dayadjusting dose right now ; in this country LiSulphate has replaced LiCarbonateWe are sad to report that Albert passed away on August 1, 2008

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24William ChristophersenAustralia71MApril 200745MND/BulbarYes50 mg 2x/day
January 15th 2008March 25, 2008Carbonate150 mg 2x/day250 mg 2x/dayFebruary 18,20080.32January 22, 20080.22February 12, 20080.3February 17, 20080.4February 26, 20080.5March 7, 2008February 26, 200845323030Rilutek 7 months, CoQ10, tamoxifen, E, C (not taking C, E, Tamoxifen or C0Q10 at the moment - awaiting PEG 3 months)1st month ALSFRS went down by 2 due to having a PEG put in, was on a waiting list for 3 months for this, condition is static.Sad to report passed away Mar. 25, 2008

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25Leo G.USA-California62MAugust-0644sALS/bulbarYes50 mg 2x/day
January 17, 2008February 9, 2008150 mg 2x/day250 mg 2x/dayFebruary 19, 20080.4January 23, 20080.3February 18, 2008January 23, 20084426namenda,remeron,cymbalta,prednisone,endocort,synthroid,hydrocodone,provigil,creatine,d-ribose,trehalose,gingkoWe are sad to report that Leo G. passed away on unexpectedly on February 9, 2008

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26Susan T.USA-NC70FMay-0633sALS/limbNo

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27JohnWCanada61MOctober-0042sALS/bulbarYes
50 mg 2x/day
January 14, 2008CarbonateAPO?150 mg 2x/day150 mg 3x/dayMarch 26, 2008<0.1January 24, 20080.3March 10, 20080.11April 30, 20080.48June 13, 2008June 13, 2008increased fatigue, slight appetite loss, nausea, and diarrhea, gone after two months4231323232323232Vits C (1500 mg),D (2000 mg),E(1600 IU),CoQ10 (800 mg),grape seed extract, allopurinol, Celebrex (200 mg) multivitamin, milk thistlearms and hands painful in the morning (was happening before starting lithium)diarrhea is gonesome loss of fine motor control, but not enough for an ALSFRS-R point drop

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28Cathy R.Canada56FO-November 200447sALS/limbNoJanuary 16, 2008Carbonate150 mg 2x/day150 mg 3x/dayJanuary 28, 2008300 mg 2x/dayFebruary 11, 2004300 mg/dayApril 15, 20080.29January 23, 20080.49February 4, 20080.35February 11, 20080.47March 3, 20080.54April 1, 20080.47June 26, 2008February 4, 2008N/AN/A4728282929282927Effexor, Alpha lipoic, MSM, Milk Thistle, Probiotics, Vitamin E, Calcium, Omega 3 Fish Oil

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29Sharon F.USA-Nebraska53FA+January-0646fALS/limbYes
50 mg 2x/day
January 17, 2008Carbonate150 mg 2x/day150 mg 3x/dayJanuary 22, 2008150 mg 4x/dayFebruary 8, 2008150 mg 3x/dayFebruary 20, 20080.3January 22, 20080.3February 8, 20080.5February 20, 2008February 20, 20084631283023juice plus, CoQ10

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30ENV39MMarch 2005sALS/limbYes50 mg 2x/day
February 4, 2008Carbonate150 mg 2x/day150 mg 3x/dayFebruary 14, 2008900 mg/dayApril 2, 20081200 mg/day<May 130.27February 14, 20080.4April 2, 20080.4?April 2, 2008none2420202020179/26/2008spent month in hospital; on trach

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31Jeff C.USA/Georgia48MNovember 200648sALS/limbYes
December 21, 2007March 2, 2008Carbonate150 mg 2x/day150 mg 3x/dayJanuary 17, 2008150 mg 4x/dayFebruary 13, 20080.11January 11, 20080.1April 2, 20080.3February 22, 2008Weakness, nausea, urgency of urination, diarrhea 48393939Baclofen, NorvascLithium discontinued on March 2, 2008 because of side effects

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32Livio V.Italy64MJune 200746sALS/limbYes50 mg 2x/day
December 28, 2007CarbonateCarbolithium150 mg 2x/day150 mg 3x/dayJanuary 23, 2008150 mg 4x/dayMarch 6, 2008150 mg 3x/dayApril 29, 20080.2January 5, 20080.23January 22, 20080.29February 16, 20080.34February 16, 20080.32April 22, 2008Maybe more fatigue and for sure reappearing fasciculations after 4 months of absencenone4643434343424242Co Q10 - Acetil L Carnitine - Eritromicin - Vitamin E Phisio 3x/week , Home Exerciseslight hand tremorslight hand tremor + increased catarrh

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33Patricia J.USA/Iowa67FMay-0747sALS/bulbarNoJanuary 17, 2008March 22, 2008Carbonate300 mg/day0.3February 8, 2008none yet4741BNG (Chinese herbs), CoQ10, Shaklee multiple vitamins, glucosamine chondroitin, lecithinMarch 22, 2008: PALS in hospital with bad cough and cold and has DISCONTINUED LITHIUM

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34Todd KUSA - Tennessee 45MJanuary-0648sALS/limbNoJanuary 10, 2008April 16, 2008Carbonate150 mg 3x/day150 mg 2x/dayJanuary 18, 2008150 mg 3x/dayFebruary 8, 2008600 mg/day
March 5, 2008900 mg/dayApril 9, 2008<0.3February 4, 2008<0.3March 4, 2008<0.3April 7, 200848212121Even though my FVC has remained the same there is no doubt I have continued to progressAt 600 mg/day lots of weakness; much more at 900 mg/day; stopped lithium on April 16. FVC declined at 71% of previous rate while on lithium.

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35Torres E.Spain54MFebruary-0545fALS/limbYes50 mg 2x/day
4528Vitamin E, Nucleo CMP Forte - Treated with stem cells in X-Cell Center (17-january) (some improvements in first week)

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36Carrol P.61FFall 200546sALS/limbJanuary 12, 2008February 21, 2008March 4, 2008Carbonate150 mg 2x/day0.35January 22, 20080.6May 20, 2008May 20, 2008 ?losing hair; pre-existing Hashimoto's thyroid46multivitamin, vit C, vit D cream, magnesium, b12 shots, folic acid shots, hgh, probiotics, omega 3, b complex, greens (powdered)stopped lithium when hospitalized for panic attack on Feb. 21. Resumed lithium & out of hospital on March 4.sudden increase in weakness week of May 19, 2008.

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37ilgal 58FJuly 200743sALS/bulbarNoJanuary 23, 2008Carbonate150 mg 2x/day150 mg 3x/dayJanuary 31, 20080.3January 28, 20080.6February 11, 20080.6March 10, 20080.6May 15, 2008February 11, 2008none43383635343432279/19/2008Quinidine/dextromethorphan, prempro, levothyroxine, toprol, multivitamin, glucosamine, calcium. Vitamin C, Vitamine E, B complex, tylenol PM, ceftriaxone or placebo (clinical trial)

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38Nobregapaulo7Brazil47MJuly-0548sALS/limbYes50 mg 2x/day
December 10, 2007Carbonate150 mg 2x/day300 mg 2x/dayFebruary 23, 20080.6December 25, 20070.5February 11, 20080.3February 22, 20080.5March 20, 20080.5March 20, 2008December 25, 2007none4823232323222222vit.E, vit.C, amitriptilina e baclofenFeels weaker but not by a full ALSFRS-R point

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39Mark M.60MMay 200647sALS/bulbarYesJanuary 22, 2008March 25, 2008liquid carbonate50 ml (300 mg)/day75 ml (450 mg)February 12, 20080.3February 11, 20080.7March 17, 2008March 17, 2008hand tremor, some digestion problems, hypothyroidism (being treated)47373637333431increased arm weakness but not enough for FRS drop

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40HSedgUSA39FFall 200548sALS/limbNoJanuary 23, 2008March 23, 2008CarbonateRoxane150 mg 2x/day300 mg 2x/day750 mg/dayFebruary 19, 20080.12February 8, 20080.33February 16, 20080.52February 26, 2008February 26, 2008483838Stopped after two months on lithium due to extreme diarrhea

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41Charlotte C. Michaud54FNovember-0540sALS/limbYesJanuary 24, 2008April 27, 2008Carbonate150 mg 2x/daynone4012154Rilutek, Baclofen, Benicar, Sertaline, Tylenol, Fexofenadine, OmeprazoleStopped lithium due to increased breathing difficulties.Charlotte is out of the hospital and on a vent

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42James EldridgeUSA47MJanuary-0348sALS/bulbar/limbYes50 mg 2x/day
January 27, 2008CarbonateRoxane150 mg 1x/day150 mg 2x/dayFebruary 4, 2008150 mg 3x/dayFebruary 21, 2008300 mg 2x/day0.3February 4, 20080.29February 18, 20080.39March 4, 20080.36April 16, 2008Depression and itchy skin are gone. Still thirsty, still extra drool, Slight extra fasciculations (reduced since last report)Cramping disappeared after start of Li. Cramping has gotten a little worse in the last week. No change noticed in condition (score)4840404040404041Bulbar and limb symptoms were simultaneous, I am a very slow progressorFeels good, all side effects goneexperiencing excess saliva, extra droolingexcessive salivamild excessive drooling

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43fanappelSweden43MMay-0442sALS/limbYes50 mg 2x/day
January 30, 2008Sulphate21 mg 4x/day21 mg 5x/dayFebruary 6, 20082*42+2*21 mg/dayFebruary 20, 20080.3February 6, 20080,4February 13, 20080.4February 20, 20080.5February 27, 20080.5March 26, 20080.5June 4, 2008February 13, 2008none42111111Rilutek + acetylcystein

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44Jim ZelosAustralia69MAugust 200546sALS/limbYes50 mg 2x/day
January 16, 2008Carbonate1/2 250 mg tab 2x/day90 mg 3x/dayFebruary 16, 2008175 mg 2x/dayMarch 2, 2008250 mg 2x/dayApril 8, 20080,3February 14, 20080.3April 3, 20080.4June 6, 2008June 6, 2008urgency to urinate and occasional loose bowel movements4634343432323230zyloprim,betaloc,avapro,baclofen,multivitamin,B12 1000mg/day,folic acid, CoQ10 400mg 2x/day,milk thistle 400 mg/day, fish oil 1000mg 3x/day glucosamine sulfate 1500 mgside effects eased a bit, no diarrhea. In hospital with deep vein thrombosis; started blood thinner.

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45Gary JensenUSA62MMarch 2007sALS/limbYes50 mg 2x/dayJanuary 31, 2008Capsules150 mg 2x/day150 mg 3x/dayFebruary 18, 2008600 mg/dayApril 2, 20080.25February 7, 20080.44February 26, 20080.33March 25, 20080.33April 1, 20080.5April 24, 2008February 26, 2008decreased thyroid -- on thyroid medication353133312424,Levothyroxin,Crestor,Zetia,Naltrextone,Doxazosin,Fluticasone,Astelin,asperin,RenewPro,N-Acetyl Cysteine,ReadiSorb,Biotin,Cinnamon,DHEA Plus,Fish Oil Concentrate...,Reducing lithium since it doesn't seem to be doing any good.

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46PoniekPoland45MOctober-0348sALS/limbNoFebruary 1, 2008April 1, 2008Carbonicum125 mg 2x/day250 mg 2x/dayFebruary 25, 2008<0.2February 25, 2008I feel weaker, not sure whether because of lithium or another reason.none483333Nothing at this moment

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47Michael FinleyUSA/Washington39MMay-06sALSNoDecember 14, 2007Carbonate250 mg 1x/daynonenone11hope for stabilization (FRS=11)

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48AHandsUSA/N. Carolina44MNovember 200742sALS/limbYesFebruary 6, 2008May 21, 2008Carbonategeneric150 mg 1x/day150 mg 2x/dayFebruary 9, 2008150 mg 3x/dayFebruary 15, 2008150 mg 4x/dayApril 3, 2008150 mg 6x/dayMay 6, 20080.1February 14, 20080.2February 21, 20080.3February 29, 20080.2March 20, 20080.2April 19, 20080.4May 21, 2008May 21, 2008temporary (48 hours) depression after increasing dosageNo longer cramping in bed424141414040379/19/2008Alpha Lipoic, CoQ10, Various Antioxidants, Vitamins and Supplementsbicycling (on road)atrophy in left hand, 2/05, atrophy in right hand fall '07Feeling lousy (as of April 19, 2008)FVC dropped to 67% (in May). Was 100% in November. I quickly run out of air when bicycling up hill. Pruitic (itchy) rash on feet for last week.

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49GabrielP62MJanuary 200743sALS/limbNoJanuary 31, 2008July 6, 2008Carbonate150 mg 2x/day150 mg 3x/dayFebruay 7, 2008150 mg 4x/dayFebruay 14, 2008150 mg 5x/dayFebruary 28, 2008900 mg/dayMarch 16, 2008300 mg/dayJuly 3, 20080.14February 5, 20080.26February 12, 20080.24February 26, 20080.27March 6, 20080.44March 26, 30080.53May 22, 2008March 26, 2008slight appetite loss and occasional constipation43363635343232309/21/2008Co-Q10(1300 mg), creatine, resveratrol, Vit C, B complex, Dwent down to 750 mg/day then back to 900. Experiencing slight appetite loss and occasional constipation.Currently reducing lithium dose by 100 mg/week bec. experiencing appetite loss, fatigue, and constipation.Stopped lithium. After stopping regained appetite and fatigue is less prounounced

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50SharonCa58FDecember-0743sALS/limbNoFebruary 1, 2008September 4, 2008Carbonate150 mg 2x/day150 mg 3x/dayFebruary 9, 2008600 mg/dayMarch 5, 2008450 mg/dayApril 1, 20080.2February 7, 20080.4February 15, 20080.3February 21, 20080.2March 5, 20080.4May 20, 20080.5July 9, 2008April 1, 2008painful cramping in legs stopped; painful cramping in hands much diminished43394040404040noneStill at FRS 40 but legs are weaker. Using walker in the house.discontinued lithium because of severe kidney infection

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51GSchoenfeldUSA53MAugust 200647sALS/limbNoFebruary 2, 2008Carbonate150 mg 2x/day150 mg 3x/dayFebruary 19, 2008300 mg 2x/dayMarch 5, 20080.2February 8, 20080.3February 29, 20080.4March~March 15, 200847252618small doses of ZoloftGulf War ALSSome loss of hair

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52mgparkcity57MSeptember 2006sALS/limbYesJanuary 17, 2007Carbonate150 mg 2x/day150 mg 3x/dayFeburary 1, 2008750 mg/dayFebruary 15, 2008300 mg 3x/dayMarch 18, 2008600 mg/dayJune 20080.2January 24, 2008<0.2January 31, 20080.2February 15, 20080.3February 26, 20080.5May 7, 20080.3June 18, 2008May 7, 2008increased weakness and slurring - swollen feet; occasional slurred speech454445434242norvasc, qualaquin, clozanapamSlurring of speech, whcih is either ALS related or due to lithium.hands and arms weakened considerably over past two monthsReduced dose from 900 to 600 mg/day to reduce slurred speech. ALS prog. continues, inc. weakness in hands & arms.

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53BWiss49FJanuary 200741sALS/limbNoJanuary 31, 2008May 4, 2008Carbonate150 mg 2x/day450 mg/dayMarch 17, 2008300 mg 2x/day0.2February 28, 20080.2March 13, 2008headache4126262515NoAtenenol, Zithromax, Mepronon antibiotic for lyme disease

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54RendadUSA46FOctober-0748sALS/bulbarYes50 mg 2x/day
February 2, 2008Carbonate300 mg 2x/day0.5March 10, 2008March 10, 2008none yet483732Vitamin E, Selenium, CoQ10, Glyconutirients, Vitamin C, Creatine, Gluthathione, Multi-vitaminincreased progression rate?went on trach and ventilator on May 13, 2008. Still taking lithium.

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55HoodyUSA, California42MApril-0647sALS/bulbarYes50 mg 2x/day
February 3, 2008Carbonate150 mg 2x/day150 mg 3x/dayFebruary 21, 2008300 mg 2x/dayMarch 18, 20080.2February 8, 20080.2February 15, 20080.3February 28, 20080.2March 6, 20080.4March 25, 20080.5June 5, 2008March 25, 2008possibly increased fasciculation, particularly in neck and nose (never had fasciculations in nose before starting Lithium)47171715151313Baclofen, Rilutek, Welbutrin, Nutropin, Diazepam, Ambien CR, Docusate Sodium, MultivitaminSlight increased fasciculationsfeeling fatiguecontinued increase in fasciculations

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56Steve GreenUSA, California43MJanuary-0446sALS/bulbarYes50 mg 2x/day
February 4, 2008CarbonateRoxana150 mg 2x/day600 mg/day0.3none46363637328/29/2008

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57FightingMomUSA32MMarch-0748sALS/limbYes50 mg 2x/day
January 1, 2008Carbonate300 mg 2x/day0.2January 10, 20080.23January 28, 20080.1April 7, 2008nonepreviously severe fasciculations dramatically slowed, speech appears better483333333330Increlex, Enalapril, Milk Thstle, DHA, multi, NAC, creatine, alpha lipoic, resveratrol, trocetrenol, omegas, etc...Added choline to help boost lithium levelsIn last month fewer fasciculations, "looks healthier", ALSFRS-R is still 33 but a "higher 33"limb weakness has progressed, but fascics still undetectable

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58JCC64MFebruary 200747sALS/limbYesFebruary 1, 2008Carbonate300 mg/day300 mg 2x/dayFebruary 19, 2008900 mg/dayMarch 5, 2008600 mg/dayMarch 19, 2008450 mg/dayApril 17, 20080.21February 8, 20080.35February 25, 20080.53March 10, 20080.38March 25, 20080.34April 7, 20080.32July 22, 2008March 10, 2008Nonone4741414141403939Vitamin D and Alpha-lipoic acid, 200 mg/daylower motor neuron MND onlyrilutek added on March 20

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59Russ ConleyUSA, California63MNovember-0642sALS/limbYes50 mg 2x/day
February 2, 2008June 15, 2008Carbonate150 mg 2x/day150 mg 3x/dayFebruary 8, 2008150 mg 4x/dayFebruary 15, 2008150 mg 3x/dayFebruary 21, 20080.3February 8, 20080.3February 13, 20080.5February 19, 20080.4February 27, 20080.4March 6, 20080.4May 14, 2008February 19, 2008weight gain aftr two months (~ 10 pounds)423938383938AM: Hydrochlorothiazide 25mg, Aciphex 20mg, Synthroid 0.125mg, Lexapro 10mg, Lipitor 10 mg PM: Baclofen 10mg, Amitriptyline 50mg, Zolpidem 10mg, Clonazepam 0.5mg, CoQ10 300mg 2x day, E 400, C 500, Omaga 3 1000, Folic acid 400I can't point to any improvement and the only progression may be in the lower FVC, but I started Lithium in between FVC tests so can't say for sure.Sometimes feels like brain fog; usually drinking more water solves the problem.Stopped lithium; breathing was down two consecutive times after starting lithium

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60Mark O.USA, Minnesota43MJuly-0644sALSYes50 mg 2x/day
January 30, 2008Carbonate300 mg/day150 mg 3x/dayFebruary 19, 2008600 mg/dayFebruary 27, 20080.21February 18, 20080.3February 27, 20080.46March 12, 20080.5March 26, 2008March 12, 2008increased saliva44353535Multi-vitamin

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61ashamp73FNovember-0637sALS/limbYes50 mg 2x/day
January 31, 2008Carbonate150 mg 2x/day0.45February 19, 2008February 19, 2008rash (gone)3732333232312727creatinine, vitamin b1 and b12, turmeric, COQ10, mycardis hcl, time-release magnesium, multi-vitamin, and fish oil

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62VCMCANADA41FO+December 200745sALS/limbNoFebruary 7, 2008CarbonateApo Lithium150 mg 2x/day150 mg 3x/dayFebruary 28, 2008600 mg/dayMarch450 mg/dayApril 9, 2008300 mg/dayApril 18, 2008150 mg/daySeptember, 20080.2February 25, 2008One week with increase fasciculation, none after45444443424031-Baclofen 20mg a day -vit B12 1000mcg/day, E 400 iu /day -Zinc 20mg/weekDiagnosed with papillary thyroid cancer on April 18. Dropped dose to 300 mg/day.Operated on for thyroid cancer. Remains on lithium.

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63Rick_6155MJanuary 200847sALS/limbYes50 mg 2x/day
February 5, 2008Carbonate150 mg 2x/day150 mg 3x/dayFebruary 14, 2008300 mg 2x/dayFebruary 21, 2008450 mg 2x/dayMarch 4, 20080.2February 12, 20080.3February 21, 20080.3March 3, 20080.7March 11, 2008March 11, 2008mild constipation47474747474747general MND diagnosis -- not clear ALS yet

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64LeeO50MSeptember-0647sALS/bulbarNoFebruary 2, 2008April 12, 2008Carbonate150 mg 2x/day300 mg 2x/dayFebruary 28, 20080.2February 18, 2008reaction to paxilswallowing better47121269/18/2008naproxen, gabapenton, ibuphrophen, paxil, prilosec.

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65ashfiebUK62MApril-0546sALS/limbYes50 mg 2x/day
December 22, 2007April 16, 2008CarbonatePlenur130 mg 3x/day300 mg/dayMarch 14, 2008400 mg/dayApril 2, 20080.23April 2, 2008some fasciculations, but not as bad as previously, none46434343434242Riluteck Pyridostigmine Vit C COQ10 Low dose Aspirinstopped Lithium Orotate on the 14th March 2008 and started the same day on Lithium Carbonate Stopping lithium after 3 months (2 on orotate, 1 on carbonate) because of rapid weakening of shoulder. Feels progression faster than before.Although ALSFRS-R score is unchanged, quite a bit worse than 6 months ago

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66mkwong37MMay-0345sALS/limbNoJanuary 29, 2008Carbonate150 mg 2x/day300 mg 2x/dayFebruary 14, 2008150mg+300mg dayFebruary 28, 20080.28February 4, 20080.56February 20, 20080.49March 10, 20080.31March 17, 20080.6April 21, 20080.32July 22, 2008February 20, 2008more fatigue and weakness4521191521191818

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67Eileen 69MOctober-0746sALS/limbYes50 mg 2x/day
January 22, 2008Carbonate150 mg 2x/day300 mg 2x/dayJanuary 29, 2008900 mg/dayFebruary 7, 2008?February 6, 20080.54March 4, 20080.53May 29, 2008March 4, 2008SLIGHT HAND TREMORS4641343026CoQ 10 300mg daily Creatine 4800mg daily Acetyl L Carnitine 450mg with Arginine 387mg daily Zoloft 200mg dailybipap set at 12.4, ready to increase to 12.8. Using more frequently; all night, plus 4 hours during the afternoon -- 2 hours previously.

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68Pasquale La TosaUSA, Florida48MAugust-0644sALS/bulbarYes50 mg 2x/day
February 9, 2008Carbonate150 mg 2x/day150 mg 3x/dayFebruary 29, 2008600 mg/dayMarch 18, 2008750 mg/dayMarch 29, 2008900 mg/dayApril 15, 20080.3February 29, 20080.2March 18, 20080.3March 29, 20080.4May 30, 2008May 30, 2008none4432343432313429None

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69JeannieUK29FA+July-0146sALS/limbNoFebruary 8, 2008June 6, 2008Carbonate250 mg 1x/day250 mg 2x/dayFebruary 22, 2008625 mg/dayMarch 12, 2008750 mg/dayApril 4, 20081000 mg/dayApril 18, 2008875 mg/dayMay 2, 2008<0.1February 15, 20080.26March 10, 20080.25April 2, 20080.29April 16, 20080.6April 25, 20080.44May 9, 2008April 25, 2008NON SO FAR46272828282828QUININE, BACLOFENStopped taking lithium on June 6, 2008; progression seems to have been faster over past 4 months.Went back to dose of 1000 mg/day on May 29, after blood reading of 0.33 on May 26.

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70DawingerUSA, MN55MApril-0747sALS/limbNoFebruary 8, 2008Carbonate150 mg 2x/day150 mg 3x/dayMarch 3, 2008150 mg 4x/day
March 8, 2008150 mg 5x/dayApril 8, 20080.2February 28, 20080.7March 13, 20080.4April 8, 20080.5June 11, 2008March 13, 2008mild headache, hand tremors, increased fasciculations474444444342.--milk thistle-b5-b12-b/complex-vit.d3-grape seed ext.-evening primrose oil-CoQ10 AIS MAX whey proteinFascics are the same, increased shaking of hands, dry mouth in the morningarms a little weaker but not much

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71hansdebreeHolland52MJune-0545sALS/limbYes50 mg 2x/day
soon45Vit. E, CoQ10, Vit. C, Vit. B, Sulfarlem

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72Matthew Fraser New Zealand36MMarch-0547sALS/limbNoFebruary 13, 2008Carbonate300 mg/day375 mg/dayFebruary 25, 2008250 mg 2x/day?0.2February 26, 20080.3March 12, 20080.3April 18, 20080.5May 15, 2008May 15, 2008none4728262525252523Chinese Herbs daily Garlic 300 mg daily Magnesium 100 mg daily Milk Thistle 300 mg daily New dawn honey 2 tbs. daily Selenium 200 mcg daily Soy Milk 500 daily Soy Protein 2 tbs. Soy lecithin 2 tbs. daily Vitamin B-6 5 mg daily Vitamin E 1000 mg daily Wheatgrass 1 tps. daily Juice, fresh veg and fruit daily

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73sh12339MApril 200737sALS/limbYes50 mg 2x/day
February 1, 2008Carbonate300 mg/day0.4February 14, 2008February 14, 200837232222CoQ10 400 mg, lutimax, omega3

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74HerdlurkyUSA, Iowa28MAB+October-0348sALS/limbNoFebruary 8, 2008Carbonate150 mg 2x/day300 mg 2x/dayApril 16, 20080.4February 22, 20080.2April 14, 20080.5May 2, 20080.5May 31, 2008February 22, 2008none481817161514Ambien, Zinc, Alpha Lipoic Acid, Silymarin, Vitamin C, Ambrotose

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75Steveh92562USA, California44MApril-0548sALS/limbYes50 mg 2x/day
February 9, 2008March 15, 2008Carbonate150 mg 2x/day>0.4February 18, 2008strange taste in mouth and esophogus -- very bad48282319Stopping lithium for two weeks starting 3/15 because of strong side effects and to recover from a bad flu infectionvery sick with the flu all month

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76Guppy33FMarch-0745sALS/limbYes50 mg 2x/day
February 8, 2008CarbonateLithicarb250 mg 2x/day250 mg 3x/dayMarch 13, 2008500 mg 2x/dayJune 23, 2008<0January 6, 2008nonefeeling a little stronger in the legs453941391200mg CoQ10 daily

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77Pat Dwyer USA, Seattle46MJune-0548sALS/limbYes50 mg 2x/day
February 8, 2008April 24, 2008Carbonate150 mg 2x/day300 mg 2x/dayMarch 15, 20080.1March 3, 20080.4April 4, 2008April 4, 2008occasional headache (not sure if related to lithium)48353632Vitamin B12, E, Magnesium, Potassium, CoQ10, Chinese herbs and Quinine for crampsStopped lithium; CO2 levels up from 43 to 55 over two months.

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78Csaba42Hungary42MApril-0745don´t knowYes50 mg 2x/day
February 9, 2008Carbonate125 mg 2x/day250 mg 2x/dayFebruary 16, 2008250 mg 3x/dayApril 5, 20080.3February 22, 20080.4April 25, 2008April 25, 2008none45393837373736rilutek2*50mg/day creatine 5-7 g /day, vitamine complex,B1 1,5g/day, polyoxidonium cure 10*6mg, vitamine C 7 g/day,Calciummagnezium, amino acids(Bcca express+amino3600), tea-x, B vitamine komplex

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79Moacir Brasil47MMay-0746sALS/limbYes50 mg 1x/dayJanuary 20, 2008CarbonateCarbolithium300 mg + 150 mg/day300 mg 2x/dayFebruary 13, 2008750 mg/day February 29, 20080.12February 8, 20080.16February 22, 20080.28April 18, 2008none4630303030302828rilutek 1x 50mg/day creatine 8g/day vitamine E 1200 ui/day vitamine C 1mg/day multivitamin Bacoflen 10 mg 2x/day tamoxifen 20mg 1x/day lithium 450 mg/dayphysio 5x/week plus home exerciseno change

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80BerciHungary51FJune-0746sALS/limbYes50 mg 2x/day
January 27, 2008Carbonate125 mg 2x/day250 mg 2x/dayFebruary 3, 2008375 mg/dayFebruary 11, 2008250 mg 2x/dayFebruary 25, 20080,37February 8, 20080.38February 18, 20080.41February 28, 20080.42March 14, 2008February 28, 2008none46444444]Vitamin E, C, bkomplex

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81Treehugger39047USA65MOctober-04sALS/limbNonot yetVALIUM 2MG FOR SLEEP, VALERIAN FOR ANXIETY, SAM-e FOR DEPRESSION

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82kaihawaiiGermany36MB+November-0745sALS/limbYes50 mg 2x/day
February 11, 2008July 18, 2008CarbonateQuilonum Retard225 mg 1x/day450 mg 1x/dayFebruary 18, 2008675 mg 1x/dayFebruary 27, 2008900 mg 1x/dayMarch 8, 20080.25February 27, 20080.37March 7, 20080.48March 19, 20080.51April 3, 20080.47April 18, 2008March 19, 2008they were gone (thirsty and very very bad, metallic taste in my mouth and also some kind of metallic smell in my nose), and dizziness after standing4545454545454342rilutek twice a day, Lyrica 75mg 3 times(Pregabalin - against muscle cramps), Magnesium 600mg / day, Vitamin E, 800mg day and Beer ;-)Physiotherapy twice a week sometimes burning eyes and more cramping of all muscles but especially in the legs (I don't now if its really a sideeffect or just progression of the disease)weaker but not by full pointweaker but not by a full point. some days bad fascics, pain, and fatigue; other days not.

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83SheronemusUSA48MMarch-0643sALS/limbYes50 mg 2x/dayFebruary 11, 2008Carbonate150 mg 2x/day150 mg 3x/dayMarch 15, 20080.2February 25, 20080.3March 10, 20080.4March 24, 20080.3April 7, 20080.8May 1, 20080.4August 19, 2008March 24, 2008none4336363636373736baclofen 10mg 1x/day; Co-Q10 600mg 4x/day

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84groottdeNetherlands59MJune-0748sALS/limbYes50 mg 2x/day
February 8, 2008CarbonatePriadel150 mg 2x/day400 mg/dayFebruary 14, 2008600 mg/dayFebruary 27, 2008800 mg/dayMarch 12, 20080.2February 14, 20080.27February 27, 20080.39March 12, 20080.51March 27, 2008March 27, 2008none484543444233I also visit a Nature scientist and I have sometimes help of an personal coache.The progress of my desease is very slowly.The functions of my hand and fingers is not well (tighten buttons or so)Arms and hands still getting weakerhands and arms still getting weakerno side effects but hands and arms and legs still getting weaker

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85Dave S.USA, Michigan35MMarch-0748sALS/limbYes50 mg 2x/dayJanuary 15, 2008March 26, 2008Carbonate300 mg 1x/day450 mg 1x/dayJanuary 15, 2008300 mg 2x/dayFebruary 1, 2008900 mg/dayMarch 1, 20080,3January 15, 20080,3February 1, 20080.3February 21, 20080.4March 25, 2008March 25, 2008Increased fasc., occasional upset stomach at start up, mild headache at start up. Restless sleep, more fasc., weaker?4842403838Started worthlesstek about two weeks after lithium, multi vit,coq10,omega 3,glyconutrientsstill have more fasc and more weakness and occasional hand tremortoo many side effects, primarily increased weakness everywhere, almost feels as though progression was sped up due to lithium......taking a break for now.....may start up again

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86DTAUSA58MOctober-9248sALS/limbNoJanuary 27, 2008April 1, 2008Carbonate375 mg 1x/day300 mg/dayMarch 13, 20080.3February 2, 20080.4February 9, 20080.4March 1, 2008February 9, 2008Upon starting, symptoms (fasciculation's, weakness, etc) accelerated, but, returned to pre-lithium levels after 2 weeks. nausea and increased urination.48998

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87ZenArcherUSA39MFebruary-0747sALS/limbYes50 mg 1x/dayFebruary 7, 2008April 21, 2008Carbonate150 mg 2x/day 150 mg 3x/dayFebruary 13, 2008150 mg 4x/dayMarch 14, 2008<0.2February 12, 20080.4February 25, 20080.3March 10, 20080.5March 24, 20080.4April 7, 20080.4April 18, 2008February 25, 2008Occasional slurred speech474545444142Coenzyme Q-10 (400 mg), N-Acetyl Cysteine (600 mg), Vitamin E (400 mg), Vitamin D (400 mg), Vitamin C (2000 mg), Blueberry Extract (2000 mg), Silymarin Milk Thistle (1200 mg), Green Tea Extract (630 mg), Vitamin B Complex (150 mg), Ginkgo Biloba (240 mg), Magnesium Oxide (250 mg), Vipocetine (20 mg), Flaxseed Oil (4000 mg), Melatonin (5 mg), Grape Seed Extract (400 mg), Acetyl L-Carnitine (1000 mg), Alpha Lipoic Acid (600 mg), Creatine (4500 mg)stopped lithium on April 21 because of a sudden change in leg strength and speech. No recovery of function as of one month after stopping.

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88gjonesUSA56MDecember-0537sALS/limbNoFebruary 13, 2008March 23, 2008Carbonate150 mg 2x/day150 mg 3x/dayFebruary 27, 2008150 mg 5x/dayMarch 7, 20080.2February 18, 20080.3February 25, 20080.25March 4, 2008constipation and headaches. Side effects so bad that lithium discontinued as of March 23, 200837181610celebrex, prozac, baclofen, coQ10, alpha lipoic acidLithium discontinued on March 23, 2008. Severe constipation and headache and faster progression.

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89LorieUSA, Alabama46FMarch-05sALS/limbsoon

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90JoeUSA38MOctober-0747sALS/limbNoFebruary 13, 2008Carbonate150 mg 2x/day300 mg 2x/dayMarch 18, 2008450 mg 2x/dayApril 23, 2008450 mg 3x/dayJuly 8, 20080.007March 18, 20080.19April 23, 20080.38July 8, 2008none4740404040383838

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91J. MacnabGreat Britain51MNovember-0743sALS/limbYes50 mg 2x/dayFebruary 9, 2008Carbonate150 mg 2x/day 150 mg 3x/dayFebruary 23, 2008250 mg/dayMay 1, 20080.19March 28, 2008none4338373329262217Co-enzyme Q-10, Grape seed extract, Vitamin B, NAC

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92Dana PUSA52FO+March-0646sALS/limbNoFebruary 14, 2008April 20, 2008Carbonate150 mg 2x/day0.3February 21, 2008increased fasciculations, fatigue, slight headacheno cramps or spasms46282810Stopped lithium on April 20, 2008. PEG operation on April 22, went on ventilator on May 8.

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93jeremy b. USA58MA+May-0747ALS/bulbarNoFebruary 14, 2008July 18, 2008Carbonate150 mg 2x/day 150 mg 3x/dayFebruary 20, 2008300 mg 2x/dayFebruary 27, 2008300 mg 3x/dayApril 9, 2008300 mg 2x/dayApril 19, 2008150 mg 2x/dayMay 31, 20080February 20, 20080.3February 27, 20080.3March 5, 20080.5April 15, 20080.3May 5, 20080.2June 21, 2008April 15, 2008upset stomach? Fatiguewife thinks handwriting is easier to read. Third month: Emotional lability gone.473028242421191.5 cans isosource and 25 mg elanil at nightVery bad side effects at 900 mg/day: upset stomach, feeling terrible. Dropped back to 600 mg/daysleeping better at night. Still not feeling as well as before going to 900 mg/day (currently at 600 mg/day)Often has an upset stomach, thought process slower.lowered lithium dose because of almost daily stomach upsetStopped on July 18: The lithium hasn't slowed progression and stomach aches are continuing. Also stopping Prevagen.

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94ErikaHungary56FFebruary-0839sALS/limbYesMarch 20, 2008July 31, 2008carbonateLithicarb?250 mg 2x/dayJune 30, 20080.27April 20, 20080.34June 16, 2008weakness393632302827baclofen

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95CMAUSA47FFebruary-07ALS/bulbarNoFebruary 29, 2008April 19, 2008150 mg 2x/day600 mg/dayMarch 17, 2008900 mg/day?750 mg/dayApril 4, 2008<0.2March 12, 20080.3April 4, 2008I've been taking Lithium since a week now and just since yesterday I started feeling weakness, and fatique34341 Mg Estrodial, 0.88mg Levothyroxine, 10 Mg Paxil, 10 Mg Zyrtec, & various Vitamins Could not tolerate 900 mg/day dose -- felt like a zombie -- wobbly walk, felt out of it

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96grob44USA-FL63MNovember-0544sALS/limbYes50 mg 2x/day
February 16, 2008May 10, 2008Carbonate150 mg 2x/day150 mg 3x/dayMarch 30, 2008150 mg 2x/dayMay 4, 20080.3February 15, 20080.4February 26, 20080.2March 18, 20080.3April 4, 20080.3April 20, 2008February 26, 2008none44282619blood pressure, diuretic, muscle relaxer, sleeping pillStopped lithium on May 10, 2008 because progression did not slow on lithium

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97Donna B.USA, Colorado51FO+May-0547sALS/limbNoFebruary 15, 2008April 23, 2008*June 18, 2008Carbonate150 mg 2x/day 150 mg 3x/dayMarch 18, 2008150 mg 4x/day
March 27, 2008150 mg/dayJune 18, 20080.3February 21, 20080.3February 28, 20080.3March 6, 20080.3March 13, 20080.38March 27, 20080.47April 3, 2008April 3, 2008headache every day for first week, then stopped. Increased saliva, twitching, & clonus; stiff & hard to walk4730303028celebrex 200mg 2xday; aciphex 30mg; zanaflex 6mg started rilutek on Feb. 15; stopped rilutek and celebrex on Feb. 29 due to elevated liver enzymes.stopped lithium because felt weaker, more fatigue, worse in generalStopped lithium on Jully 6, 2008, just 2 wks after restarting; very stiff and weak, esp. hips and shoulders. Lithium not working for me.

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98ctflaUSA49MJanuary-0646sALS/limbYes50 mg 2x/day
February 15, 2008August 15, 2008Carbonate300 mg/day600 mg/dayFebruary 15, 2008750 mg/dayApril 23, 20080.2February 8, 20080.3April 13, 20080.50.56June 20, 2008~May 2008none4619191918181818baclofen,floxetine,protonix,claratindecreased pseudo-bulbar effect -- less laughing and crying innapropriately

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99RENNIESOUTH AFRICA 51MMay-0145sALS/limbNoJanuary 14, 2008August 15, 2008CAMCOLIT400 mg/day600 mg/dayApril 19, 2008750 mg/day?600 mg/day
May 22, 2008400 mg/dayMay 31, 20080.4February 19, 20080.3April 18, 20080.5May 13, 20080.7May 20, 20080.3August 2, 2008February 19, 2008none4521222221212421600MG TEGRETOL, 400MG NEURONTIN, 20MG LORIEN, 10MG FOLATE, 80MG DIOVAN (valsartan), 200MG N-ACETYL CYSTEINE, 20MG VITAMIN B COMPLEX Hplanning to experimentally stop on Aug. 15

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100ireckonUSA46MJanuary-0647sALS/bulbarYes50 mg 2x/dayFebruary 14, 2008Carbonate150 mg 2x/day150 mg 3x/dayFebruary 26, 2008150 mg 4x/dayMarch 7, 20080.17February 21, 20080.21February 28, 20080.26March 6, 20080.4March 13, 2008March 13, 2008saltwater taste in mouth. More energy at 300 and 450 mg but less energy at 600 mg. Initially spasms & fascics but cleared up.4743434141414140get b12 shots, co10, multivatimsstrong fasciculations on and offside effects not noticeable anymorstopped rilutek on 8/16 because of diziness.

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101ArgiaSpain30MJune-0747sALS/limbYesFebruary 19, 2008Carbonate150 mg 2x/day200 mg 2x/dayMarch 4, 2008150 mg 3x/dayMarch 18, 2008600 mg/dayApril 11, 20080.23February 28, 20080.28March 13, 20080.33April 10, 2008Increased fasciculation, Urgency to pee4743434133

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102BKKCanada54MNovember-0645sALS/bulbarNoMarch 7, 2008March 29, 2008Carbonate300 mg/day450 mg/dayMarch 27, 20080.2March 25, 2008none4522We are sad to report that BKK passed away on unexpectedly on March 29, 2008

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103Gene S59MSeptember-0646sALS/limbYes50 mg 2x/dayFebruary 15, 2008July 28, 2008Carbonate150 mg 2x/day150 4x/dayJune 23, 2008>0.5February 25, 20080.4March 25, 20082.7May 2, 20081.7May 7, 20080.4June 12, 20080.3June 23, 2008March 25, 2008?nearly reached lithium toxicity when food, water intake curtailed by swallowing difficulties46211813111111BACLOFEN, FLOMAX, SERTRALINE, WARFARIN, VITAMIN C, VITAMIN E, VITAMIN B COMPLEX, CENTRUM SILVER, BETA CAROTENE, WALFINATE, ALBUTEROLWe are sad to report that Gene passed away on Sept 1, 2008lithium was stopped because blood level was measured at 2.7 on May 2. Measured at 1.7 on May 3lithium was stopped from May 2-10 bec. of a toxicity episode (Gene was not eating or drinking prior to a feeding tube operation)Feeding tube inserted this month. Lithium stopped for surgery; now back on 450 mg/day, blood level of 0.4 on June 12.

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104crokayUSA77MFebruary-0242sALS/limbYes50 mg 2x/day
February 14, 2008Carbonate300 mg/day0.6March 11, 20080.4April 2, 20080.7April 30, 2008March 11, 2008nonefeel better42232022232022provigil 100mg qd.,celebrex 200mg qd., co-q10 600mg qd

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105SHANOAUSTRALIA50MAugust-0746ALS/bulbarYes50 mg 2x/dayFebruary 14, 2008March 3, 2008Carbonate250 mg 2x/day0.6February 25, 2008February 25, 2008I HAVE HAD AN UPPER BODY HEAT RASH FOR 6 MONTHS, THAT SUDDENLY GOT WORSE AT ABOUT THE TIME I STARTED463235Baclofen 10mg Creatine 20mg Omega 3 4000 Zinc 125 B Complex 1 Garlic 900 Vitamin C 2000 Flaxseed 4000 Burdock Root 1400 Silymarin/ St Marys Thistle 700 Grape Seed 100 Ginger 1000 Water 3.5ltStopped 3/3/08 due to severe rash that started immediately. Started Baclofen same day as Lith and now think it is the Bac that is causing rash. Have stopped Bac and will restart Lith if rash subsides

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106WolfbaneUSA48MNovember 200747sALS/limbYes100 mg/dayFebruary 21, 2008April 1, 2008April 24, 2008Carbonate150 mg 2x/day150 mg 3x/dayMarch 19, 2008150 mg 2x/dayMay 1, 2008150 mg 3x/dayMay 22, 2008600 mg/dayJune 2, 2008900 mg/dayAugust 21, 2008<0.2March 19, 2008<0.2July 14, 20080.4August 25, 2008August 25, 2008No side effects as far as 4747474747474747vitamins, omega 3, Vitamin D3Went off of lithium for several weeks for liver check. Severe cramps in leg when went off; cramps went away when started again.I have noticed that my cramping has reduced significantlyslight visual effects. Some difficulty focusing after taking dose, usually gone in 45 minutes.suffered pericarditis; lithium dose temporarily down to 450 mg/day

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107RuleBoyUSA54MMay-0548sALS/limbYes50 mg 2x/dayFebruary 10, 2008August 9, 2008Carbonate150 mg 2x/day150 mg 3x/dayFebruary 20, 2008300 mg 2x/dayFebruary 29, 2008<0.1February 18, 20080.2February 28, 20080.4March 11, 20080.4March 27, 20080.4April 25, 20080.5July 14, 2008March 11, 2008none4833333333333130cymbaltamight be a bit weaker although FRS is unchanged. Slow progressor.ALSFRS-R score same but subtle deteriorationstopped lithium just short of the six month point. A little less clonus since stopping.

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108Pajo13HUNGARY61MMarch-0645sALS/bulbarYes50 mg 2x/day
January 30, 2008Carbonate150 mg 2x/day150 3x/dayFebruary 13, 2008375 mg/dayFebruary 22, 2008150 mg 2x/dayMarch 28, 20080.360.33February 5, 20080.67February 19, 20080.58March 21, 2008none4529292422antidepressant

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109Brian J. USA, CA57MJuly-0743sALS/limbNoFebruary 15, 2008Carbonate300 mg 2x/day0.5February 19, 20080.5February 27, 20080.4March 5, 20080.5March 12, 20080.5April 8, 20080.6June 9, 2008February 19, 2008mild upset stomach433131302927

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110RWhitlockNC, USA58MNovember-7848sALS/limbNoJanuary 29, 2008April 29, 2008Orotate720 mgs occasionally slight headache and nausea 482322Fish oil X6 CoQ10 100mgs X4 Astragalus X3 Grape seed extract X3 Milk Thistle Extract 600mg X3 Green Tea extract X3 Tumeric X3 Lecithin X1 Dolomite X9 Coral Calcium X4 Burdock Root X3 Vit E 400 iu X6 Vit C 500 mgs X1 Vit B Complex 50mgs ½ X2 Cell Forte (Inositol) X3 Evening Primerose oil X3 Vit D X1 Vit B15 X1 Teavigo X4 150mg egcg Acetyl L-Carnitine HCl 500mg X1 N-Acetyl Cysteine 600mg X2 After meals under tongue B12 methylcobalamin 1000mcg sublingual x2Stopped lithium on April 29 because not effective (after some improvements over the first two weeks).

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111DaddyOUSA, Georgia47MSeptember-0644ALS/bulbarNoFebruary 22, 2008Carbonate150 mg 2x/day300 mg 2x/dayApril 24, 2008900 mg/dayMay 20, 20081200 mg/dayJune 18, 2008600 mg/dayJuly 25, 20080.2February 29, 20080.1March 10, 20080.2March 17, 20080April 24, 20080.23May 4, 20080.5June 16, 2008June 16, 2008dry mouth, increased fasciculationsMuch less cramps in neck (yawning) - No lump in throat - Voice clearer - Able to type with left hand - Able to write better - decreased saliva/drooling and increased appetite4434353534343534Ambien 10mg, Ritalin 10mg......supplements: B complex, vitaman E, multil-vitamanleft hand can type fast but it hurtsstill have dry mouth but fasciculations have decreased.

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112Boiler Fan USA67MJuly-0744ALS/bulbarYes50 mg 2x/day
February 18, 2008Carbonate150 mg 2x/daynone4441other vitamins and minerals

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113togosUSA, California49MDecember-0547sALS/limbYes50 mg 2x/dayFebruary 22, 2008Carbonate150 mg 2x/day300 mg 2x/dayApril 1, 2008300 3x/dayMay 1, 2008300 2x/dayMay 21, 20080.2March 11, 2008?March 25, 20080.2April 1, 20080.3May 1, 20080.4May 21, 2008May 21, 2008none47434040multivitamin, calcium supplementlegs noticeably weaker over last 45 days. Still walking but with a lot of effort.

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114Bosque2805USA64FMarch-0541sALS/limbYes50 mg 2x/day
February 15, 2008April 20, 2008Carbonate150 mg 2x/daynone413635Multivitamin, B12, ALAlithium stopped because weakness increased rapidly, particularly in arms and breathing

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115SmoothSUSA, Georgia 39MA-October-0645sALS/limbNoMarch 4, 2008Carbonate150 mg 2x/day150 mg 3x/dayMarch 19, 2008300 mg 2x/dayApril 8, 2008750 mg/dayApril 30, 2008300 mg 2x/dayMay 7, 20080.3March 10, 20080.2March 18, 20080.3April 8, 20080.4April 15, 20080.6May 6, 2008none45252221noneno side effects but increased clonus noticeable. Possible slowing of sx.

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116TrixieCanada, AB48FJuly 200641sALS/bulbarNoFebruary 23, 2008CarbonateLiCarb300 mg/day4118CoQ10, Acupuncture

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117Maureen eUSA62FJuly-0536sALS/limbYes50 mg 2x/dayFebruary 6, 2008Carbonate150 mg 2x/day300 mg 2x/dayMarch 10, 2008450 mg/dayApril 7, 2008600 mg/day
April 10, 2008450 mg/dayApril ?600 mg/dayMay 15, 20080.1February 20, 20080.2March 26, 20080.2April 3, 20080.2April 22, 20080.12April 30, 20080.4May 18, 2008May 18, 2008Soft bowl movements -- starting to feel less tired.. also have diarrea361916182117coq10, effexor xr, lorezepam, mucinex, multi-vitamin, naltrexone, norvasc, qualaquin, senna, zetia, ursodiol, provigilfeeling fatiqued went from 450 mg to 600 mg on March 10; felt fatigued; went back to 450 mg, then went back to 600 on April 10horrible tiredness, considering stopping lithium. Current 600 mg/day, 0.3 blood level on 6/1I am pretty sad! - Humberto

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118Penn State Mike34MNovember-0744ALS/bulbarYes50 mg 2x/day
February 21, 2008Carbonate150 mg 2x/daynone4444VITAMIN C (3000mg daily), VITAMIN E (400 IU daily), BETACAROTENE (25,000 IU daily), CoEnzyme Q10 (300mg daily)

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119StuCANADA57MMarch-0744sALS/limbYes50 mg 2x/dayFebruary 25, 2008May 25, 2008CarbonateCarbolith150 mg 2x/day150 mg 3x/dayMarch 6, 20080.2February 29, 20080.4March 14, 20080.5April 4, 20080.5May 6, 2008March 14, 2008headache and nausea for first three days (gone), abdominal cramps, increased urination - legs and trunk a little weaker. Less steady walking and on the stairseye lid fasciculations stopped, tears no longer burn eyes, feet are no longer cold, and legs are slightly stronger443231282624Effexor XR 37.5mg, COQ10- 100mg, Creatine - 5 grams, Selenium - 50mg, Vitamin E - 1200U, Vitamin C - 1000mg, Vitamin A - 12,500U, Cod Liver Oil - 10minims Naproxen 2x 500mgLithium stopped on May 25 due to side effects and accelerated progression of ALS symptoms.

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120Patrick66MAugust 200647sALS/bulbarYesJanuary 23, 2008~April 13, 2008camoclite tab250 mg 2x/day250 mg 1x/dayFebruary 5, 2008181.5 mg/dayFebruary 25, 20080.8January 29, 20080.4February 5, 20080.55February 25, 2008February 5, 2008THIRSTY ALL THE TIME, A SMALL RASH THAT LASTED ABOUT TWO WEEKSA LITTLE EASIER TO SWALLOW SIPS OF WATER4799stopped lithium because hospitalized with high liver enzymes. May restart later.We are sorry to report to that Patrick passed away on May 19.

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121GasmanWales, UK49MDecember-0544sALS/limbYes50 mg 2x/dayFebruary 17, 2008CarbonateLithosun150 mg 2x/day150 mg 3x/dayMarch 6, 2008300 mg 2x/dayMarch 20, 2008750 mg/dayApril 7, 2008900 mg/dayApril 29, 20080.11February 22, 20080.15February 29, 20080.22March 11, 20080.27March 18, 20080.39April 15, 20080.5July 18, 2008May 8, 2008loose but regular stools, increased fasciculations?4422222222222221Ca, Mg, Zn, grape seed extract, ginseng, Vits C and E, CoQ10, ginger, tumeric, rosemary, ccreatine, colustrum, alpha lipoic acid, reservatrolIncreased fascics in first month settled down. Loose but regular stools. Increased emotional lability?Increased cramps and clonus. Fasciculations reduced to pre-lithium levels.increased clonus and cramps

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122Kenny AUSA36MFebruary-0347sALS/limbYes50 mg 2x/day
February 25, 2008Carbonate150 mg 2x/day450 mg/dayFebruary 25, 20080.3March 7, 20080.3March 14, 20080.3March 21, 20080.6April 9, 2008April 9, 2008The only side-effects I had were headaches, nausea and diarhea for the first 2 weeks. No problems since471718I take zyrtec 10mg daily amitriptyline 100mg daily lexapro 10mg daily baclofen 10mg daily zanaflex 16mg daily nexium 20mg daily marinol 7.5mg daily COQ10 200mg daily vitamin E not sure mg vitamin C 1200mg daily grape seed extract 50mg daily vitamin B12 1000mg daily

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123gamboachuckUSA70MNovember-0429sALS/limbYes50 mg 2x/dayFebruary 26, 2008Carbonate150 mg 2x/day600 mg/dayMay 31, 20080.17February 29, 20080.19March 7, 20080.2March 14, 20080.28May 19, 20080.49June 10, 20080.47September 2, 2008June 10, 2008not experienced any noticeable effects, positive or negative2920202023192221increase in salivation and yawningJune 10: Reached 0.49 mmol/l and experienced increased fasciculations in legs and arms.increased fascics in arms and thighs. Dreams extend into consciousness for 10 to 15 minutes after waking,Blood level 0.6; increased sleepiness according to wife.

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124nedvCANADA53MOctober-0545sALS/limbYes50 mg 2x/day
February 13, 2008Carbonate150 mg 2x/day450 mg/dayMay 17, 20080.2May 17, 20080.4August 20. 2008 ?August 20, 2008?occasional nausea/hot flushes4524242523232022low dose naltrexone. Amytripteline. Folic acid. Medical marijuanadry, flaky skin on face

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125LeedxUSA/California61MA+April 200740sALS/limbNoFebruary 27, 2008CarbonateRoxane Labs150 mg 2x/day150 mg 3x/dayMarch 14, 20080March 4, 20080March 11, 20080.3March 18, 2008HEADACHE, FATIGUE4027159/16/2008multi-vitamins, vitamin C

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126Removed intentionally

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127revivaUSA59MJune-0446sALS/limbYes50 mg 2x/dayFebruary 26, 2008Carbonate150 mg 2x/day450 mg/day0.6March 26, 2008March 26, 2008none463130cytoxan,minocin,azithromycin,ivermectin,alpha lipoic acid, acetyl=L-carnitine,omacor

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128ShannonUSA62MDecember-0446sALS/limbYes50 mg 2x/day
February 28, 2008April 23, 2008Carbonate150 mg 1x/day150 mg 2x/dayFebruary 28, 2008150 mg 3x/dayMarch 12, 20080.2March 12, 20080.4April 2, 20080.4July 3, 2008April 2, 2008none46333334Nexium, Sertraline HCL, Alprazolam ERlithium stopped due to increased depression and trembling of hands

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129cheryilynUSA50FSeptember-0642sALS/bulbarYes50 mg 2x/dayFebruary 29, 2008May 15, 2008Carbonate150 mg 2x/day0.4March 7, 2008March 7, 2008n/a4211zoloft 100mg 1x baclofen 10mg 3x glyburide 5mg 2x metformin 500mg 2x lisinapril 5 mg 1x glycopyrrol 1 mg 2x gemfibrozil 300mg 2x omeprazole 20 mg 2x furosemide 20 mg 1x docusate sodium 100mg 2x aspirin ..81mg 1x vit e 400mg 1x vit c 1000mg 1x fish oil 1000mg 1x tylenol 1000mg 2xStopped lithium on May 15 after being admitted to the hospital for pneumonia. Didn't go back on bec. didn't want to deal with headaches again. Also suffered severe headaches when lithium was stopped.

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130Roy J. GromlichUSA65MFebruary-0640sALS/limbYes50 mg 2x/day
February 16, 2008Carbonate150 mg 2x/day450 mg/dayMarch 13, 20080.4February 28, 20080.3March 13, 20080.4March 26, 20080.5April 9, 20080.5May 14, 20080.7June 25, 2008February 28, 2008Possibly increase urination - nothing else so far - WEAKNESS, LETHARGY, POOR CONCENTRATION, SWOLLOWING DIFFICULTIESstrength of legs, lower back and sides Easier time sitting & standing Easier time eating, chewing & swallowing - less coughing and choking403031282828Q-10 400 mg/day and Vit E - 400 IU/dayNeck strength is better - easier lifting head and holding. Chewing and swallowing is nearly normal for 1st time in 6 months or more. Fingers are better - easier to type this week than last week or the week beforeNot feeling too good - weakness, tiredness, difficulty chewing and swallowing food. Tremor in right hand at times -- fasics in both legstired, aching, out of focus. Difficulty standing from bed and chair. Severe constipation.

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131BunkyUSA62FJanuary-0546sALS/limbYes50 mg 2x/dayFebruary 29, 2008July 30, 2008August 15, 2008CarbonateEskalith150 mg 2x/day450 mg/dayMarch 22, 2008300 mg/day450 mg/dayMay 30, 2008150 mg/dayAugust 15, 2008450 mg/dayAugust 30, 20080.2March 6, 20080.3March 13, 20080.2March 20, 20080.3March 27, 20080.4April 3, 20080.4October 2, 2008April 3, 2008Increased urinations, increased muscle weakness, and fatigue4640404040404040CoQ10 1200 mg/day Lorazapam 0.5 mg 2/day hand tremors lessened and not feeling as weak after lowering dose from 450 to 300 mg/day on May 10.extreme fatigue and constant urination less, but experiencing hand tremors and weakness in both hands and armsWent down dosage, and then back up to 450 mg/day for two weeks. Side effects now much reduced, especially the weakness in hands & arms.still hand tremor, but much reduced; some weakness in arms, but mainly after exercise. Some feet swelling past two weeks.stopping lithium for 2 weeks to see if arm weakness and tremors are due to lithium or ALS progression

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132SCHEMERA24USA, Connecticut34MSeptember-0647sALS/bulbarNoFebruary 21, 2008Carbonate150 mg 2x/day450 mg/dayMarch 31, 2008300 mg 2x/dayApril 13, 2008>0.2March 25, 20080.4May 9, 20080.5June 25, 2008May 9, 2008eyes burn on occasion4740424241434038BACLOFEN, ELAVIL, CQ 10, VITAMIN E, ORGANIC DIET, CHOLOCAL, PAROTID, AND DHEAno side effectsexperiencing burning eyesswollen ankles, burning eyesswollen feet and burning eyes

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133Richard AtkinsonGERMANY46MJune-0645sALS/limbYes50 mg 2x/dayFebruary 15, 2008CarbonateHypnorex retard200 mg 2x/day200 mg 3x/dayFebruary 28, 20081000 mg/dayMarch 7, 2008800 mg/dayMarch 27, 20080.2February 28, 20080.29March 7, 20080.66March 27, 2008March 27, 2008very itchy dry skin in the face but this may come from the penacilin after I fell down and they had to stich up my face45333433Rilutek since July 2007 2 x 50mgI will be going tomorrow to a rehabilitation center for 3-4 weeks

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134professorcraigUSA48MDecember-0747sALS/bulbarYes50 mg 2x/day
February 21, 2008Carbonate150 mg 2x/day0.1February 27, 2008none4740600 MG cOq10, Multivitamin

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135OregonWayneUSA51MFebruary-0743sALS/limbNoMarch 1, 2008Carbonate150 mg 2x/day150 mg 3x/dayMarch 28, 2008600 mg/dayApril 8, 20080.3March 20, 20080.3April 8, 20080.3April 22, 20080.5May 8, 2008increased fasciculations, urination4337373736363635Vitamin E, Beta Carotene, Creatine, Vitamin C, Apple cider vinegar tabletsNausea on dosage increase for a couple of days. Sleep disorder on dosage increase for a couple of daysthirsty, salty taste in mouth, frequent urinationstill increased urinationstill thirst and increased urination

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136wfullerUSA47MDecember-0545sALS/limbYes50 mg 2x/day
February 28, 2008Carbonate150 mg 2x/day375 mg/dayMarch 10, 2008450 mg/dayMarch 24, 2008525 mg/dayMay 7, 2008600 mg/dayAugust 30, 20080.34March 6, 20080.39March 14, 20080.41March 20, 20080.39April 30, 20080.47May 14, 20080.38August 27, 2008March 30, 2008none4537373736353433multivitamen, C, E, CO10, asprin, glucasamin

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137Fotios TzimasGREECE48MMarch-0447sALS/bulbarNoFebruary 29, 2008March 22, 2008SulphateLithiofor330 mg 2x/dayNo474Increlex (IGF-1), Natural Cranberry with Vitamin C, Aloe Vera Drinking GelStopped lithiujm in order to go back on Saroten

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138BarbaraUK58FMay-0546sALS/limbYes50 mg 2x/day
March 6, 2008CarbonatePriadel200 mg/day400 mg/day?600 mg/dayMay 8, 20080.4March 31, 20080.4April 21, 20080.5May 19, 2008March 31, 2008nonefeels calmer, and significantly less stiffness464343434343Other medications:- attenelol, losartin, cozaar, thyroxine, baclofen, valium (occasionally for muscle spasm), oxybutynin, niaspan, HRT Supplements:- Q10, pycnogel (grapeseed extract), alpha-lipoic acid, vitamin C, vitamin EDiagnosis is PLS; very slow progressionUnlike many of the other PALS I find lithium completely without problems

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139EdwinUSA, Colorado60MAB+May-0640sALS/limbNoFebruary 27, 2008CarbonateRoxane150 mg 2x/day150 mg 3x/dayMarch 5, 2008150 mg 4x/dayMarch 20, 2008150 mg 5x/dayApril 7, 2008150 mg 6x/dayApril 21, 20080.1March 4, 20080.2March 19, 20080.2April 4, 20080.4April 28, 20080.4June 17, 20080.4August 4, 2008April 28, 2008after moving up to 600MG/day I now have mild headaches, cramps, hand tremors, muscle weakness4033323130282826. I am on 5 grams of Androgel (1% testosterone gel) daily and my testosterone level and liver enzymes were last checked (and are ok) on 2/12/2008side effects subsided as of April 4side effects subsided in early April

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140TagAUSTRALIA46FMay-0648sALS/limbNoMarch 4, 2008August 16, 2008Carbonatelithicarb250 mg/day750 mg/dayMarch 27, 2008500 mg/dayApril 14, 2008250 mg/dayJuly 17, 20080.3March 24, 2008<0.4April 1, 2008No48191818171615Currently reducing lithium dosage in preparation for a stem cell transplant in India

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141BluUSA65MJuly-0646sALS/limbYes50 mg 2x/dayFebruary 29, 2008Carbonate150 mg 2x/day>0.3March 21, 2008none464037403637CoQ10 1000 mg Amino Acids Milk Thistle Chromiium Picobinate Alpha Lipoic Acid 300mg B 12 Complex with C 750 mg B 12 1000 mcg Beta Carotene 25000 iu Coral Calcium1500 mg DHEA 25 mg Flax Seed Oil 1000 mg Grape Seed Extrac 100 mg L-Carnitine 1000 mg L-Lysine 500 mg Melatonin 3 mg Paba 100 mg Selenium 200 mcg Vitamin C 1/4 tblsp 1000 mg Vitamin E 1000 iu Boran 3 mg Chondroitin Glucosamine 1tbsp 1500 mg Dong Qua 550 mg Holy Basil 900 mg L-Theanine 100 mg Magnesium Citrate 1 tbls sp 400 mg NAC 1200 mg Taurine 500 mg Vitamin D 1000 iu Phosphadyl Serine 100 mg Tumeric AshwagandaNexium 40 mg Rilutek 100 mg Cymbalta 30 mg Amitriptyline 25mg Baclofen 10 mg Lisinopril 10 mg Metoprolol (tartrate) 50 mg Lithium carbonate 300 mg Zantac 150mg

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142JanieSOUTH AFRICA57FJune-0541sALS/UnsureNoMarch 4, 2008March 21, 2008CarbonateQuilonum450 mg/dayfelt weaker, couldn't even pick up a spoon, very weak breathing at night4127vit E, B12, Cstopped lithium in middle of first month because felt weaker, and very weak breathing at night

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143FOX TROTTERSUSA37MMay-0738sALS/limbYes50 mg 2x/dayOctober 29, 2007Orotate300 mg/day300 mg 3x/day?0.5March 18, 20080.4March 25, 20080.5April 18, 20080.5May 9, 2008March 18, 2008some weakness and can't get to sleep quickly (noted after month 4)38353535some weakness and can't get to sleep quickly

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144KrisncrashAUSTRALIA47MSeptember-0743sALS/limbNoMarch 8, 2008Carbonate250 mg 2x/day0.4March 12, 20080.4March 26, 20080.41May 9, 20080.39June 7, 20080.4August 12, 2008March 12, 2008none4336373429292828speech is worse and walking is becoming difficultFrequent urination and increased walking issuesfrequent urinating and balance and walking issuse

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145RickCUSA58MO-October-0746sALS/limbYes50 mg 2x/dayMarch 6, 2008July 3, 2008Carbonate150 mg 2x/day150 mg 3x/dayMarch 12, 20080.3March 12, 20080.5March 18, 20080.4May 19, 2008March 18, 2008No46424141383232. I began rilutek on March 5, 2008. I also take 12.5mg of hydrochlorothiazide daily. I take 25mg of benadryl or 2.5mg of diazapam each night as a sleep aidNo change in ALSFRS-R but rapid progression of weakness in right arm and back and neck musclesStopped on July 3 because progression continues to speed along, no apparent benefit.

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146KensilCANADA68MNovember-0648sALS/RespiratoryNoMarch 7, 2008August 17, 2008Carbonate150 mg 2x/day150 mg 3x/dayMarch 28, 2008150 mg 4x/dayMay 29, 20080.2March 11, 2008?March 17, 20080.4April 22, 20080.3May 27, 20080.4June 26, 2008April 22, 2008maybe going to bathroom more often because of upped consumption of water only been on Li for 1 day4826282628252624Cold FX and Low Dose Naltrexone and Tylenol Arthritus more fatigue, desire to nap more oftenfatigue, more pronounced fasciculations, and weaker when walkingStill experiencing more fatigue during the day. No let up in decline. Legs are weakening, and more frequent and pronounced fasciculations.The more profound and frequent fasciculations have stopped. Hardly any fasciculations at all.Planned lith stop on August 17. I feel that I am progressing more rapidly than at any time before taking lithium.

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147lgstotUSA59MOctober-07ALS/bulbarYes50 mg 2x/day
March 10, 2008Carbonate150 mg/day750 mg/dayApril 3, 2008300 mg 3x/dayApril 15, 20080.5April 2, 20080.3June 4, 2008April 2, 2008none41403835Tropine 0.4 MGsomewhat fatigued, napping more

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148aloha1USA50MSeptember-0648sALS/bulbarYes50 mg 2x/dayMarch 10, 2008March 25, 2008Carbonate150 mg 2x/dayweakness, fatigue, dullness of mind, not alert, stomach upset, increased urination, difficulty breathing482315CQ10, Magnesium, Fish Oil, Mulit-vitamumDiscontinued after 300 mg/day for 14 days due to severe side effects. Problems began improving after stopping lithium.

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149PhilskiAUSTRALIA43MDecember-0745ALS/bulbarYes50 mg 2x/day
February 21, 2008Carbonate250 mg 2x/day250 mg 3x/dayMarch 11, 2008250 mg 4x/dayMarch 21, 20080.3February 26, 20080.3March 11, 20080.4March 20, 20080.4March 29, 2008March 20, 2008some fasciculations after increase to 250 mg 4x/day, stopped after 4-5 days454543Milk Thistle, Fish oil, Multivitamins, Grape seed, Antioxidant tabs, magnesium supplementJaw cramps on yawning, which had become common, have completely stopped since taking Lithium

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150quilterUSA53FO+September-0443sALS/limbNoMarch 3, 2008Carbonate150 mg 2x/day300 mg 2x/dayMarch 10, 20080.1March 10, 20080.6March 24, 20080.6April 8, 20080.7April 15, 20080.6July 2, 20080.2September 2, 2008March 24, 2008none43313131313435Synthroid, Citalapram, Muti-vitamin, Vitamin C

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151TitusCANADA56MNovember-0746sALS/limbNoJanuary 24, 2008CarbonatePMS150 mg 2x/day150 mg 3x/day
February 7, 2008150 mg 4x/day
March 1, 20080.2February 4, 20080.3February 26, 20080.3March 26, 20080.4April 25, 2008April 25, 2008nonedecrease in fasciculation, less cramping, less spastic finger movements 4645454545454545

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152SAKHGERMANY31FO+September-0646sALS/limbNoMarch 6, 2008June 3, 2008CarbonateHypnorex Retard800 mg/day0.38March 19, 20080.69April 17, 2008April 17, 2008None so far462828282727Gingko biloba, Vitamin E, Selenium, Asparkam (Mg and K source)Stopped taking rilutek on March 21unstable mood, more spasticity, more talking difficultystopped lithium; experiencing more slurring of speech and unstable mood.

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153midwestUSA/midwest64MA+April 200645sALS/limbNoMarch 13, 2008July 12, 2008Carbonate150 mg/day300 mg/dayMarch 20, 2008450 mg/dayApril 3, 2008150 4x/dayMay 14, 2008450 mg/dayJune 13, 20080.1March 20, 20080.2March 27, 20080.4April 10, 20080.3May 8, 20080.4May 22, 20080.4May 29, 2008April 10, 2008increased freuency pf urination, fatigue, swelling of the feet, 4543434240Baclofen 20mg/day,COQ10 -300 mg/day,L-taurine-200mg/day,Calcium supplements,Alpha Lapoic acid -100mg/day, Omega3 -1 teaspoonincrease in urination and some weaknessStopped taking lithium. Experiencing no improvements, and having side effects of increased urgency to urinate, fatigue, and swelling of feet.

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154grampsUSA/Texas53MApril 200732sALS/limbYes100 mg/dayJanuary 7, 2008Carbonate450 mg/day322722

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155Vicki S60FA+September-0746sALS/limbYes50 mg 2x/day
March 13, 2008April 15, 2008Carbonate150 mg 2x/daynone4642Januvia, Cymbalta, Enablex

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156NannerUSA/MI58FO+December-9944sALS/limbYes50 mg 2x/day
March 13, 2008July 12, 2008Carbonate150 mg 2x/day0.4April 4, 20080.3April 10, 20080.3July 10, 2008April 4, 2008none4418181516warfin 5mg daily x 6 days, 7.5mg daily x 1 day; zoloft 100mg daily; omega 3 daily; multi-vitamin dailyStopped lithium on July 12. Speech worse, progression more rapid, weaker.

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157Mary Ann W.USA, Mass.52FNovember-0644sALS/limbNoFebruary 29, 2008March 29, 2008Carbonate150 mg 2x/day0.2March 3, 2008First week headaches and nausea, but have subsided442620baclofen, klonopin, tylenolStopped after one month due to side effects

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158SundanceUSA, Colorado63MO+May 199844sALS/limbNoFebruary 27, 2008July 14, 2008carbonatelithicarb300 mg/day300 mg 2x/dayMarch 20, 20080.2March 9, 20080.4March 25, 20080.4April 25, 20080.3April 22, 20080.3June 19, 2008March 25, 2008fasciculations in week 244242424242424baclofen, ambien CR, zoloft, lipitor, vit D, C, fish oil, B complex, CoQ10range of motion once a week, acupuncture, massage on alternate weeksseems a little stonger using joystick on power chair- seems to control it better than pre-lithium. Fingers haven't worked for a long time so he uses palm of hand to move joystick. Stopped on July 14 because dizzy, weak, nauseous, and faint after regular dose. Happened twice. Problems gone after stopping lithium.

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159papadun195354MAugust 200548sALS/limbYes50 mg 2x/day
March 10, 2008August 10, 2008Carbonate150 mg 2x/day450 mg/dayMarch 26, 2008600 mg/dayApril 15, 20080March 10, 20080.3March 19, 20080.3March 26, 20080.4April 3, 20080.4April 15, 20080.6May 27, 2008April 3, 2008none483129252121189/26/2008CoQ10 1600 mg, B12 1000 milligrams, vitamin C 1000 mg, vitamin D 1000 mg , selenium 500 mg,vitamin E 800 milligramsStopped lithium on August 10 because of surgery. Appetite is much better now.

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160john33AUSTRALIA56MJuly-0548sALS/limbYes50 mg 2x/day
March 12, 2008Carbonate250 mg/day500 mg/dayMarch 30, 20080.3April 26, 20080.7April 17, 2008none482929

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161joelcCANADA55MAugust-0547sALS/limbNoMarch 12, 2008March 26, 2008Carbonate150 mg 2x/day0March 5, 2008Neck pain/fatigue, headaches, increased urination, increased stiffness in hands/fingers472215Quit after two weeks because of severe side effects, especially breathing. Now on trach & vent.

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162RustyUSA, California68FJanuary 200743bulbarNoMarch 20, 2008June 30, 2008carbonate150 mg/day4324lexapro, reglan, saltropinerestless leg syndrome at nightJune 30, 2008: "Rusty" is unresponsive, resting peacefully under hospice care.

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163debi cUSA, Florida42FB+March 200645fALS/bulbarNoMarch 14, 2008carbonateEskalith150 mg 2x/daynone4522synthroid, 112 mg, zoloft, 100 mg, 1000 mg Vit C, multi vit

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164 Li2CO3CANADA64MMay-0748sALS/limbYes50 mg 2x/day
March 7, 2008Carbonate150 mg 2x/day300 mg/dayMarch 8, 2008450 mg/dayApril 7, 20080.24March 30, 20080.43April 29, 20080.35June 3, 20080.41September 4, 2008April 29, 2008No negative nor positive side-effects are noticeable4841393938353520 mg Amitriptyline per day to help me sleepAlthough ALSFRS-R is the same as last month decline is continuingNo positive or negative effects for the first 3 months. Decline appears to be continuing at the same pace as before starting lithium.

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165gchatlosUSA51MNovember-0347sALS/bulbarYes50 mg 2x/day
March 10, 2008June 3, 2008Carbonate150 mg 2x/day150 mg 3x/dayApril 5, 20080.2March 31, 20080.2April 30, 2008none4781058Hyoscyamine Glycolax Prevacid Dextropromorphan 30mg Quinidine 30mg Lodrane 24 E Fluocinonide Amitiza Desonide lotion .05%Doctor stopped lithium on June 3, 2008 due to elevated liver function test.

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166Bob Brintz USA59MMay-0748sALS/limbNoMarch 24, 2008July 10, 2008Carbonategeneric capsule 150 mg 2x/day300 mg 2x/dayApril 8, 2008>0.3March 31, 20080.4April 14, 2008April 14, 2008After second month: slowness, slightly slurred speech, possible muscle weakness48434341393939Zetia (cholesterol) Finasteride (benign enlarged prostate) Beta Carotene CoQ10 Fish Oil (Omega 3 Fatty Acid) Melatonin/Theanine Multiple Vitamin Vitamin B Complex Vitamin B12 Vitamin C Vitamin E AspirinSTopped lithium on July 10 becasue of lithium study and ALSTDI findings and because of continued progression at the same or faster rate.

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167handcrankkingUSA58MMay 200748sALS/limbYes50 mg 2x/day
March 20, 2008May 10, 2008Carbonate150 mg 2x/day300 mg 2x/dayApril 10, 2008450 mg 2x/dayApril 26, 20080.1April 3, 20080.2April 16, 20080.4<May 10, 2008~May 1, 2008increased weakness, increased fasciculations, urinary urgency4840393611/3/2008Aciphex, vytorin, liprinisol, diclofenac, suppliments - vitamine E, C, Magnesium, folic acid, Glucossmine, MSM, Cod liver oilStopped lithium on May 10 due to side effects. Elevated liver enzymes found ~May 21.Very noticeable weakness in legs and torso.stopped on May 10 because of side effects

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168ElizabethOxford, UK57FOctober 200746sALS/bulbarNoFebruary 1, 2008carbonatepriadel600 mg/daydry skin4641404141

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169becausesurrey bc CANADA47MMarch-0535sALS/limbNoMarch 20, 2008April 27, 2008June 1, 2008Carbonate150 mg 2x/daynone3522effexor 75mglithium stopped April 27 - May 31 because of interactions with effexor.

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170ShakyUSA51MFebruary-0843fALS/bulbarYes50 mg 2x/day
March 26, 2008Carbonate150 mg 2x/day0.6April 16, 20080.4August 28, 2008April 16, 2008occasional burning of eyes434039363230CoQ10 1200 mg daily, multi vitamin, B50, vit e, vitamin c, alpha lipoic acid twice daily, vit d, vit k, mucinex twice daily, and long term prevacid for gerd and dexedrine for adhdburning eyesstill burning eyes

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171LNCUSA, NY51MJuly-0743sALS/limbYes50 mg 2x/day
March 13, 2008Carbonate150 mg 2x/day300 mg 2x/dayApril 19, 20080.2April 26, 2008none433737Quinine ( qualaquine) 324mg daily,. Celexa, 20mgs daily., Rilutek 50mg twice daily.

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172DSmithUSA48MA+April-0448sALS/limbNoMarch 31, 2008Carbonate150 mg 2x/daynone4831

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173OnwardUSA54MMay-0745sALS/limbNoFebruary 7, 2008Carbonate150 mg 2x/day150 mg 3x/dayMay 15, 20080.2April 17, 20080.2May 15, 2008noneless fasciculations, less cramping, less saliva452933332827baclofen, nortriptylin, lithium carbonate, multivitamin, Vit E

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174MALVINKAHUNGARY69FJune-0743sALS/limbNoApril 4, 2008May 16, 2008Carbonate125 mg 2x/day250 mg 2x/dayApril 10, 2008375 mg/dayMay 5, 20080.69April 22, 2008none433636Q10,B KOPMLEX,C,E stopped on May 16, 2008; "antibiotikum"

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175klrkkentUSA, Ohio40M?October 200546sALS/limbYes50 mg 2x/day
April 2, 2005Carbonate150 mg 2x/day450 mg/dayApril 15, 2008600 mg/dayApril 30, 20080.3April 9, 20080.3April 24, 20080.4May 6, 20080.4June 10, 2008May 6, 2008none 4619202018191718baclofen 20 mg 4x/day, paxil 20 mg, pantoprazole 40 mg, coQ10 600 mg, vit C 1000 mg, vitamin E 800 iu, multi-vitamin

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176PDADDYUSA, California55M?April 200845sALS/limbYesApril 4, 2008Carbonate150 mg 2x/day0.1April 4, 20080.1April 11, 20080.2April 18, 20080.2May 28, 20080.2August 13, 2008May 6, 2008none45454438

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177MrcleanNetherlands54MO+October-0748sALS/limbYes50 mg 2x/day
April 7, 2008Carbonate400 mg/day400 mg 2x/dayApril 17, 2008200 mg 3x/dayApril 25, 2008500 mg/dayJune 15, 2008600 mg/daySeptember 1, 20080.3April 11, 20080.8April 18, 20080.5April 25, 20080.3September 1, 2008April 18, 2008nead to urinate more484141404037. Further I take vitamin E, Omega 3,6,and 9 and a supplement called Stemenhance.more tired than beforethyroid went from 2.7 on May 19 to 4.9 on June 6, 2008

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178Tom MUSA51MA+August-0844sALS/limbNoMarch 31, 2008Carbonate150 mg 2x/day150 mg 3x/dayApril 9, 2008600 mg/dayApril 19, 2008750 mg/dayMay 8, 20080.2April 7, 20080.3April 16, 20080.4April 25, 20080.3May 20, 20080.4June 25, 20080.4August 12, 2008April 25, 2008Vision problem on 2nd day for 1/2 hour then cleared up. Mild metallic taste. 4445454444444443Multivitamin, E, C, B12 CoQ10, Omega3. mild hand tremor

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179PhilatmUSA53MDecember-0746sALS/limbYes50 mg 2x/day
April 10, 2008June 7, 2008Carbonate150 mg 2x/day150 mg 3x/dayApril 24, 2008300 mg 2x/dayMay 8, 2008300 mg 3x/dayMay 22, 20080.1April 21, 20080.14May 5, 20080.19May 19, 20080.27June 4, 2008none464341Baclofin 10mg 3x/day, Valium 2mg 3x/day, Zesttoretic 10/12.5 1x/day, Vitamin C 3000mg/day, Magnesium 410mg/day, Saw palmetto 1000mg/day, one-a-day multiple vitamin increased leg weakness with increased dosageAt 900 mg/day experienced severe fatigue and weakness in legs. Stopped lithium on June 7. Blood level on June 4=0.27.

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180sanscottCanada57FO April 200448sALS/limbYesMarch 18, 2008Carbonate300 mg 2x/day0.4April 2, 20080.4May 11, 2008April 4, 2008none481010108Cq10, Vit C, b, e, Cranberry, stool softeners, Paxil, Acidophilus, Omega 3 Serina laxative, multivitamin, furosemide, metformin, paroxetine, celebrex, omeprazole, altaceIn hospital all month with pseudenomas infection

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181PBBUSA49MAB+February-0546sALS/bulbarYes50 mg 2x/day
April 6, 2008Carbonate150 mg 2x/day100 mg/dayAugust 9, 2008No4622212424242323Plavix, protonix, ativan,

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182mitchfirstUSA58MO+February-0847sALS/bulbarYes50 mg 2x/day
March 27, 2008Carbonate150 mg 2x/day450 mg/dayMay 19, 20080.4April 10, 20080.38July 24, 20080.4May, 2008April 10, 2008none474544444343CoQ10, B complex vitamins

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183jhallowellUSA44MO+August-0348sALS/bulbarNoMarch 17, 2008Carbonate300 mg 2x/day600 mg 2x/dayMarch 31, 20080.044March 24, 20080.12March 31, 20080.33April 8, 2008tired, loss of appetite & my concentration when writing is challenged.4816150 mg/day of amitripyline & 1000 mg 2x a day of Metformin for my diabetes.

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184TullnutUSA, Nevada56MO+September-0647sALS/limbYes20 mg 2x/dayFebruary 25, 2008Carbonate150 mg 2x/day 300 mg 2x/day0.1March 13, 20080.4April 4, 20080.4May 15, 20080.5August 7, 2008April 4, 2008none474141404039CoQ-10 1800mg/day for ALS.. Other meds include citalopram 40mg/day, saw palmetto, levothyroxine0.15mg and aspirin 81mg dailyexperiencing excessive sweating

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185panamokapalUSA45FA+December-0548sALS/limbYes50 mg 2x/day
April 12, 2008Carbonate150 mg 2x/day150 mg 3x/dayApril 29, 2008600 mg/dayMay 24, 2008450 mg 2x/dayJune 13, 20080.13April 29, 20080.22May 24, 20080.36June 13, 20080.47July 1, 20070.57August 4, 2008bad taste in mouth48383838383636paxil, ambien, baclofen, baby aspirin, tramadol/ vit c, a, e , d, coq10,creatine,nac,al lip acidALSFRS-R same this month but several things close to changing.

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186majestik12USA31MAugust-0848sALS/limbYes50 mg 2x/dayFebruary 1, 2008August 3, 2008Carbonate150 mg/day750 mg/day<May0.21March 4, 20080.27March 13, 20080.39March 20, 20080.24May 28, 200848393534333028multi vit, acai, coQ10, b12

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187luvthechiefs42FA-April-0840fALS/limbYes50 mg 2x/day
April 14, 2008Carbonate450 mg/day600 mg/dayMay 12, 2008750 mg/dayMay 16, 20080.2April 22, 20080.3April 30, 20080.3May 14, 2008a little dry mouth and maybe bad taste. that's it. i did have one brief experience the first day where i was very *aware* of my tongue. one shouldn't be aware of one's tongue. weird. it passed quickly and has not returned404040400mg of CoQ10 and a multivitaminankles and feet swelling badly

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188Tamatik64MJanuary 200844sALS/bulbarYes100 mg/dayApril 1, 2008September 1, 2008Carbonate300 mg/day450 mg/dayApril 18, 20080.2April 7, 2008<0.2April 14, 20080.35May 12, 20080.45July 10, 2008July 10, 2008drwosiness immediately after taking a tab42424343stopped lithium because of great stomach discomfort

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189cbustosSpain46FMay 200746sALS/bulbarYes50 mg 2x/dayApril 19, 2008Carbonatemagistral300 mg/day450 mg/dayApril 30, 20080.19April 25, 20080.35May 6, 20084627mTizanidine (Sirdalud), Noni juice, coQ10, multivitamin

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190linbUSA63FA+February 200845sALS/bulbarNoApril 10, 2008Carbonate450 mg/day150 mg/dayAugust0.3May 6, 2008with increase from 300 to 450 deep fasciculations, feeling of unwellness, mood down. Felt better on 300 mg.453930Went off lithium for a month; was rageful and crying all day at 450 mg/day. Now on 150 mg/day.

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191MarieCanada 52FO+September 200547sALS/limbNoMay 16, 2008Carbonate150 mg 2x/day 450 mg/dayJune 7, 20080.3May 28, 20080.3June 4, 20080.4June 18, 2008June 18, 2008feelings of nausea473939Mutli B vitamins (100mg), B12 (75mg), C(4000mg) D (1000 IU), E(400 IYU), zinc (10 mg), magnesium citrate (10 mg), magneisum chloride (5 ml), COQ10 (300 mg) ALA-R(300 mg) Grapeseed, Gingko Bliboa, Liver detox, blueberry capsurles, cod liver oil (5 ml) fish oil (10 ml), melotonin (6 mg)

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Click on the link below to calculate your ALSFRS and ALSFRS-R - today, after 1st, 2nd, 3rd ... month on lithium.

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ALS Functional Rating Scale [ALSFRS] and ALS Functional Rating Scale-Revised [ALSFRS-R]

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http://www.outcomes-umassmed.org/als/alsscale.cfm

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[1] sporadic = sALS familial = fALS bulbar = bALS