| | | | | | | | | . | 4/7 | @ San Francisco | Road Grays | L | 6-10 | Jeff Suppan | Tim Lincecum | Day | . | 4/8 | @ San Francisco | Blue Alternates | W | 4-2 | Yovani Gallardo | Randy Johnson | Night | . | 4/9 | @ San Francisco | Blue Alternates | L | 1-7 | Manny Parra | Matt Cain | Day (late afternoon) | . | 4/10 | v. Chicago | Home Whites | W | 4-3 | Braden Looper | Rich Harden | Day (late afternoon) | . | 4/11 | v. Chicago | Home Whites | L | 5-6 | David Bush | Carlos Zambrano | Night | . | 4/12 | v. Chicago | Home Whites | L | 5-8 | Jeff Suppan | Ryan Dempster | Night | . | 4/13 | v. Cincinatti | Blue Alternates | L | 6-7 | Yovani Gallardo | Edinson Volquez | Night | . | 4/14 | v. Cincinatti | Blue Alternates | L | 1-6 | Manny Parra | Bronson Arroyo | Night | . | 4/15 | v. Cincinatti | Home Whites | W | 9-3 | Braden Looper | Micah Owings | Night | . | 4/17 | @ New York | Road Grays | L | 4-5 | David Bush | Livan Hernandez | Night | . | 4/18 | @ New York | Blue Alternates | L | 0-1 | Yovani Gallardo | Johan Santana | Day | . | 4/19 | @ New York | Blue Alternates | W | 4-2 | Jeff Suppan | Nelson Figueroa | Day | . | 4/21 | @ Philadelphia | Blue Alternates | L | 4-11 | Manny Parra | Jamie Moyer | Night | . | 4/22 | @ Philadelphia | Road Grays | W | 3-1 | Braden Looper | Joe Blanton | Night | . | 4/23 | @ Philadelphia | Road Grays | W | 6-1 | David Bush | Cole Hamels | Day | . | 4/24 | @ Houston | Blue Alternates | W | 5-2 | Yovani Gallardo | Felipe Paulino | Night | . | 4/25 | @ Houston | Road Grays | W | 9-8 | Jeff Suppan | Mike Hampton | Night | . | 4/26 | @ Houston | Blue Alternates | L | 2-3 | Manny Parra | Russ Ortiz | Day | . | 4/27 | v. Pittsburgh | Home Whites | W | 10-5 | Braden Looper | Jeff Karstens | Night | . | 4/28 | v. Pittsburgh | Home Whites | W | 6-5 | David Bush | Paul Maholm | Night |
|
| | | | | | | | | . | 4/29 | v. Pittsburgh | Blue Alternates | W | 1-0 | Yovani Gallardo | Ian Snell | Day | . | 4/30 | v. Arizona | Home Whites | W | 4-1 | Jeff Suppan | Max Scherzer | Night | . | 5/1 | v. Arizona | Retro Friday | L | 2-5 | Manny Parra | Jon Garland | Night | . | 5/2 | v. Arizona | Home Whites | L | 1-4 | Braden Looper | Dan Haren | Night | . | 5/3 | v. Arizona | Home Whites | W | 4-3 | David Bush | Yusmeiro Petit | Day | . | 5/4 | @ Pittsburgh | Blue Alternates | W | 7-4 | Yovani Gallardo | Paul Maholm | Night | . | 5/5 | @ Pittsburgh | Road Grays | W | 8-5 | Jeff Suppan | Ian Snell | Night | . | 5/6 | @ Cincinatti | Blue Alternates | W | 15-3 | Manny Parra | Bronson Arroyo | Night | . | 5/7 | @ Cincinatti | Road Grays | L | 5-6 | Braden Looper | Micah Owings | Night | . | 5/8 | v. Chicago | Home Whites | W | 3-2 | David Bush | Randy Wells | Night | . | 5/9 | v. Chicago | Blue Alternates | W | 12-6 | Yovani Gallardo | Ryan Dempster | Night | . | 5/10 | v. Chicago | Home Whites | L | 4-2 | Jeff Suppan | Sean Marshall | Day | . | 5/12 | v. Florida | Home Whites | W | 6-3 | Manny Parra | John Koronka | Night | . | 5/13 | v. Florida | Home Whites | W | 8-6 | Braden Looper | Ricky Nolasco | Night | . | 5/14 | v. Florida | Home Whites | W | 5-3 | David Bush | Josh Johnson | Day | . | 5/16 | @ St. Louis | Road Grays | W | 1-0 | Jeff Suppan | Adam Wainwright | Day | . | 5/17 | @ St. Louis | Blue Alternates | W | 8-2 | Manny Parra | Todd Wellemeyer | Day | . | 5/18 | @ St. Louis | Blue Alternates | W | 8-4 | Braden Looper | Kyle Lohse | Night | . | 5/19 | @ Houston | Road Grays | W | 4-2 | David Bush | Mike Hampton | Night | . | 5/20 | @ Houston | Blue Alternates | L | 4-6 | Yovani Gallardo | Wandy Rodriguez | Night |
|
| | | | | | | | | . | 5/21 | @ Houston | Road Grays | W | 4-3 | Jeff Suppan | Roy Oswalt | Night | . | 5/22 | @ Minnesota | Road Grays | L | 3-11 | Manny Parra | Kevin Slowey | Night | . | 5/23 | @ Minnesota | Blue Alternates | L | 2-6 | Braden Looper | Anthony Swarzak | Night | . | 5/24 | @ Minnesota | Road Grays | L | 3-6 | David Bush | Scott Baker | Night | . | 5/25 | vs. St. Louis | Home Whites | W | 1-0 | Yovani Gallardo | Chris Carpenter | Day | . | 5/26 | vs. St. Louis | Home Whites | L | 1-8 | Jeff Suppan | Adam Wainwright | Night | . | 5/27 | vs. St. Louis | Home Whites | L | 2-3 | Manny Parra | Todd Wellemeyer | Day |
|